Leaflet PANADOL DUO 200mg / 500mg film-coated tablets


Indicated for: pain; fever

Route of administration: oral

Substance: ibuprofen + paracetamol (nonsteroidal anti-inflammatory drug + analgesic and antipyretic)

ATC: M01AE52 (Musculo-skeletal system | Antiinflammatory and antirheumatic products, non-steroids | Propionic acid derivatives)

Precautions:
Hepatotoxicity
Hepatotoxicity

This medicine may affect the liver.

Major drug interactions
Major drug interactions

This medicine may have important interactions with other medicines.

Nephrotoxicity
Nephrotoxicity

This medicine may affect the kidneys.

Pregnancy warning
Pregnancy warning

Use during pregnancy only on medical advice.

Bleeding risk
Bleeding risk

This medicine may increase the risk of bleeding.

Ulcer / gastrointestinal bleeding
Ulcer / gastrointestinal bleeding

This medicine may increase the risk of ulcer or gastrointestinal bleeding.

Ibuprofen and paracetamol are two active ingredients commonly used in combination to treat mild to moderate pain and fever. This combination is effective in relieving headaches, muscle pain, dental pain, menstrual pain, and other types of discomfort, providing complementary analgesic and antipyretic effects.

Paracetamol is an analgesic and antipyretic that reduces pain and fever, being well-tolerated by most patients. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation, pain, and fever by inhibiting the synthesis of prostaglandins, substances involved in the inflammatory process. Together, these substances provide more effective pain and inflammation relief than using either one alone.

Although this combination is effective, its use should be approached with caution. Ibuprofen may cause gastrointestinal side effects, such as stomach irritation, heartburn, or ulcers, especially with long-term use. Paracetamol, if overused, can harm the liver. It is important for patients to follow the recommended dosage and avoid alcohol consumption during treatment.

This combination is available over the counter, but patients should adhere to usage instructions and avoid long-term use without consulting a doctor. If pain or fever persists for more than a few days, medical advice is necessary to identify the cause and adjust the treatment.

General data about PANADOL DUO 200mg / 500mg

  • Substance: ibuprofen + paracetamol
  • Date of last drug list: 01-07-2024
  • Commercial code: W70327001
  • Concentration: 200mg / 500mg
  • Pharmaceutical form: film-coated tablets
  • Quantity: 10
  • Product type: generic
  • Prescription restrictions: OTC - Over the Counter = medicines that do not require a prescription.

Marketing authorisation

  • Manufacturer: ZAKLADY FARMACEUTYCZNE POLPHARMA S.A. - POLONIA
  • Holder: HALEON ROMANIA S.R.L. - ROMANIA
  • Number: 15474/2024/01
  • Shelf life: 2 years

Pharmaceutical forms available for ibuprofen + paracetamol

Concentrations available for ibuprofen + paracetamol

  • 200mg/500mg
  • 400mg/325mg