OPTISULIN 100U / ml solution for injection in vial medication leaflet

A10AE04 • insulin glargine • Alimentary tract and metabolism | Insulins and analogues | Insulins and analogues for injection, long-acting

Insulin glargine is a long-acting basal insulin used to control blood sugar levels in people with type 1 and type 2 diabetes. It is an insulin analog, meaning its structure has been modified to provide a slow and steady release of insulin throughout the day, mimicking the natural basal insulin secretion of the pancreas.

Insulin glargine begins to work approximately 1-2 hours after injection and provides a consistent effect for up to 24 hours or longer, without a pronounced peak of action. It is typically administered once daily, at the same time each day, to ensure stable long-term blood sugar control. It is often used in combination with rapid-acting insulins or other antidiabetic medications to manage postprandial (after-meal) blood sugar levels.

While insulin glargine is effective, its use requires caution. Hypoglycemia (excessively low blood sugar) is the most common side effect, especially if the dose is too high or meals are skipped. Other side effects may include injection site reactions, such as redness, swelling, or itching. It is important for patients to regularly monitor their blood sugar levels and follow the dose prescribed by their doctor.

Insulin glargine should be administered as directed by a doctor, and patients should use proper injection techniques. If severe side effects or difficulties in blood sugar control occur, immediate medical attention is necessary. Patients should also be aware of the signs of hypoglycemia and have a source of fast-acting sugar readily available.