Leaflet ONKOTRONE 2mg / ml concentrate for solution for injection


Indicated for: cancer

Route of administration: injectable

Substance: mitoxantrone (antineoplastic agent)

ATC: L01DB07 (Antineoplastic and immunomodulating agents | Cytotoxic antibiotics and related substances | Anthracyclines and related substances)

Mitoxantrone is an antineoplastic agent used for the treatment of acute myeloid leukemia, non-Hodgkin's lymphomas, and advanced prostate cancer. It works by intercalating into DNA and inhibiting its synthesis, leading to tumor cell death.

The medication is administered via intravenous infusion, usually in treatment cycles, with the dose adjusted based on the patient's weight and response to therapy. Common side effects include nausea, vomiting, myelosuppression, and alopecia.

Mitoxantrone is contraindicated in patients with severe hepatic impairment or hypersensitivity to the active substance. Its use also requires careful monitoring of cardiac function and blood counts.

This medication is an effective option for the treatment of hematological cancers and other tumor types, helping to improve patient outcomes.

General data about ONKOTRONE 2mg / ml

  • Substance: mitoxantrone
  • Date of last drug list: 01-05-2026
  • Commercial code: W70296002
  • Concentration: 2mg / ml
  • Pharmaceutical form: concentrate for solution for injection
  • Quantity: 1
  • Product type: generic
  • Price: 645.59 RON
  • Prescription restrictions: P-RF - Medicines prescription that is retained in the pharmacy (not renewable).

Marketing authorisation

  • Manufacturer: BAXTER ONCOLOGY GMBH - GERMANIA
  • Holder: BAXTER HEALTHCARE S.R.L. - ROMANIA
  • Number: 8636/2016/02
  • Shelf life: 3 years

Pharmaceutical forms available for mitoxantrone

Concentrations available for mitoxantrone

  • 20mg/10ml
  • 2mg/ml

Compensation lists for ONKOTRONE 2mg / ml Baxter

G14 (C1) - Multiple sclerosis

Price

Copayment

Patient

645.59 RON

645.59 RON

0.00 RON

GX (C1) - GENERIC (used in compensation list, C1, for another diagnosis)

Price

Copayment

Patient

645.59 RON

645.59 RON

0.00 RON

NHP 3 (C2) - NHP oncology

Price

Copayment

Patient

645.59 RON

645.59 RON

0.00 RON

NHP 9.1 (C2) - Spinal cord transplant

Price

Copayment

Patient

645.59 RON

645.59 RON

0.00 RON