Fertility warning
This medicine may affect fertility.
Leaflet NILOTINIB ZENTIVA 200mg capsules
Precautions:
Cytotoxic / special handling
Handle with special care.
Contraception required
Effective contraception is required during treatment.
Contraindicated during breastfeeding
Do not use this medicine while breastfeeding.
Contraindicated during pregnancy
Do not use this medicine during pregnancy.
Avoid grapefruit
Avoid grapefruit and grapefruit juice.
Hepatotoxicity
This medicine may affect the liver.
Major drug interactions
This medicine may have important interactions with other medicines.
Myelosuppression / agranulocytosis
This medicine may lower blood cell counts.
Additional monitoring
This medicine is subject to additional monitoring.
Requires periodic laboratory tests
Periodic laboratory tests may be required during treatment.
Severe skin reactions
Stop taking the medicine and seek urgent medical help if a severe rash occurs.
Cardiac risk / QT prolongation / arrhythmias
This medicine may increase the risk of heart rhythm disturbances.
Nilotinib is a medication used for the treatment of Philadelphia chromosome-positive chronic myeloid leukemia (CML). It belongs to the class of tyrosine kinase inhibitors and works by blocking the activity of abnormal proteins that drive cancer cell growth.
The medication is taken orally, usually twice daily on an empty stomach. The dose is adjusted based on the patient's condition and response to treatment. Common side effects include nausea, fatigue, headaches, and skin rashes.
Nilotinib is contraindicated in patients with hypersensitivity to the active substance or any of its excipients. It should also be used with caution in patients with cardiac or hepatic conditions.
This medication is an important option for patients with CML, helping to control the disease and improve their quality of life.
The medication is taken orally, usually twice daily on an empty stomach. The dose is adjusted based on the patient's condition and response to treatment. Common side effects include nausea, fatigue, headaches, and skin rashes.
Nilotinib is contraindicated in patients with hypersensitivity to the active substance or any of its excipients. It should also be used with caution in patients with cardiac or hepatic conditions.
This medication is an important option for patients with CML, helping to control the disease and improve their quality of life.
General data about NILOTINIB ZENTIVA 200mg
- Substance:
- nilotinib
- Date of latest medicines list:
- 01-06-2026
- Product code:
- W70537001
- Concentration:
- 200mg
- Pharmaceutical form:
- capsules
- Quantity:
- 28
- Product type:
- Generic medicine
- Price:
- 2003.07 RON
- Prescription status:
- P-RF — Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.
Concentrations available for nilotinib
- 150mg
- 200mg
- 50mg