Leaflet NEXOBRID 5g powder and gel for gel

Indicated for: wound debridement

Route of administration: cutaneous

Substance: bromelain proteolytic enzyme concentrate (enzyme)

ATC: D03BA03 (Dermatologicals | Enzymes | Proteolytic enzymes)

Proteolytic enzyme concentrate with bromelain is used for the treatment of inflammation and edema associated with trauma or surgical procedures. Bromelain, an enzyme extracted from pineapple, has anti-inflammatory properties and helps reduce swelling and pain.

This supplement is taken orally, usually in the form of tablets or capsules, with the dose adjusted based on the severity of the condition. Possible side effects include gastrointestinal disturbances, allergic reactions, and diarrhea.

Bromelain concentrate is contraindicated in patients with an allergy to pineapple or other active substances in the composition. It should also be used with caution in patients taking anticoagulants, as it may increase the risk of bleeding.

This product is a natural option for managing inflammation and edema, aiding in faster recovery after trauma or surgical procedures.

General data about NEXOBRID 5g

  • Substance: bromelain proteolytic enzyme concentrate
  • Date of latest medicines list: 01-06-2026
  • Product code: W61294001
  • Concentration: 5g
  • Pharmaceutical form: powder and gel for gel
  • Quantity: 1
  • Product type: Original
  • Price: 5459.89 RON
  • Prescription status: P-RF - Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.

Marketing authorisation

  • Manufacturer: HÄLSA PHARMA GMBH - GERMANIA
  • Holder: MEDIWOUND GERMANY GMBH - GERMANIA
  • Number: 803/2012/02
  • Shelf life: 3 years

Concentrations available for bromelain proteolytic enzyme concentrate

  • 2g
  • 5g
PDF icon EMA leaflet
Published: 07/01/2013
Updated: 03/12/2025