Leaflet NAVELBINE 10mg / ml solution for injection

Indicated for: cancer

Route of administration: injectable

Substance: vinorelbine (antineoplastic agent)

ATC: L01CA04 (Antineoplastic and immunomodulating agents | Plant alkaloids and other natural products | Vinca alkaloids and analogues)

Precautions:
Fertility warning
Fertility warning

This medicine may affect fertility.

Dose adjustment in hepatic impairment
Dose adjustment in hepatic impairment

Dose adjustment may be needed in liver disease.

Cytotoxic / special handling
Cytotoxic / special handling

Handle with special care.

Contraception required
Contraception required

Effective contraception is required during treatment.

Contraindicated during breastfeeding
Contraindicated during breastfeeding

Do not use this medicine while breastfeeding.

Contraindicated during pregnancy
Contraindicated during pregnancy

Do not use this medicine during pregnancy.

Hepatotoxicity
Hepatotoxicity

This medicine may affect the liver.

Major drug interactions
Major drug interactions

This medicine may have important interactions with other medicines.

Myelosuppression / agranulocytosis
Myelosuppression / agranulocytosis

This medicine may lower blood cell counts.

Additional monitoring
Additional monitoring

This medicine is subject to additional monitoring.

Requires periodic laboratory tests
Requires periodic laboratory tests

Periodic laboratory tests may be required during treatment.

Severe skin reactions
Severe skin reactions

Stop taking the medicine and seek urgent medical help if a severe rash occurs.

Vinorelbine is a chemotherapy medication used for the treatment of various types of cancer, including non-small cell lung cancer and advanced breast cancer. It belongs to the vinca alkaloid class and works by inhibiting tubulin polymerization, which leads to the arrest of cell division and ultimately tumor cell death.

Vinorelbine is administered intravenously or orally, depending on the type and stage of cancer, and the dosage is adjusted based on body weight and patient response. Treatment is usually given in cycles to allow the body to recover between doses.

Common side effects include nausea, vomiting, fatigue, alopecia, and myelosuppression (reduction in blood cell counts). In rare cases, severe adverse reactions such as peripheral neuropathy or liver function impairment may occur.

Patients receiving vinorelbine should be regularly monitored for hematologic function and signs of toxicity. The medication is an important option in cancer treatment, helping to reduce tumor size and prolong patient survival.

General data about NAVELBINE 10mg / ml

  • Substance: vinorelbine
  • Date of latest medicines list: 01-01-2015
  • Product code: W03901001
  • Concentration: 10mg / ml
  • Pharmaceutical form: solution for injection
  • Quantity: 10
  • Product type: Original
  • Prescription status: S - Medicines dispensed with a restricted medical prescription, reserved for use in certain specialized fields.

Concentrations available for vinorelbine

  • 10mg/ml
  • 20mg
  • 30mg
  • 50mg/5ml
  • 80mg