Leaflet NATULAN 50mg capsules

Indicated for: cancer

Route of administration: oral

Substance: procarbazine (antineoplastic agent)

ATC: L01XB01 (Antineoplastic and immunomodulating agents | Other antineoplastic agents | Methylhydrazines)

Precautions:
Fertility warning
Fertility warning

This medicine may affect fertility.

Dose adjustment in hepatic impairment
Dose adjustment in hepatic impairment

Dose adjustment may be needed in liver disease.

Cytotoxic / special handling
Cytotoxic / special handling

Handle with special care.

Contraception required
Contraception required

Effective contraception is required during treatment.

Contraindicated during breastfeeding
Contraindicated during breastfeeding

Do not use this medicine while breastfeeding.

Contraindicated during pregnancy
Contraindicated during pregnancy

Do not use this medicine during pregnancy.

Hepatotoxicity
Hepatotoxicity

This medicine may affect the liver.

Major drug interactions
Major drug interactions

This medicine may have important interactions with other medicines.

Myelosuppression / agranulocytosis
Myelosuppression / agranulocytosis

This medicine may lower blood cell counts.

Additional monitoring
Additional monitoring

This medicine is subject to additional monitoring.

Requires periodic laboratory tests
Requires periodic laboratory tests

Periodic laboratory tests may be required during treatment.

Severe skin reactions
Severe skin reactions

Stop taking the medicine and seek urgent medical help if a severe rash occurs.

Procarbazine is an antineoplastic agent used in the treatment of certain types of cancer, such as Hodgkin's lymphoma and other malignant neoplasms. It works by interfering with DNA and RNA synthesis, thereby inhibiting tumor cell growth.

The medication is taken orally, as directed by a doctor, usually as part of a combination chemotherapy regimen. It is important for patients to follow the treatment plan and undergo regular tests to monitor the therapy's effects.

Patients should be aware of potential side effects, such as nausea, vomiting, bone marrow suppression, or allergic reactions. It is important to inform the doctor of any unusual symptoms.

Common side effects include nausea, vomiting, and bone marrow suppression. In rare cases, severe reactions such as secondary leukemia or allergic reactions may occur. Patients should be informed of these risks before use.

General data about NATULAN 50mg

  • Substance: procarbazine
  • Date of latest medicines list: 01-06-2026
  • Product code: W59766002
  • Concentration: 50mg
  • Pharmaceutical form: capsules
  • Quantity: 50
  • Product type: Generic medicine
  • Price: 1243.07 RON
  • Prescription status: P-RF - Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.

Marketing authorisation

  • Manufacturer: HAUPT PHARMA AMAREG GMBH - GERMANIA
  • Holder: CN UNIFARM S.A. - ROMANIA
  • Number: 450/2019/02
  • Shelf life: 3 years

Compensation lists for NATULAN 50mg Unifarm

NHP 3 (C2) - NHP oncology

Price

Copayment

Patient

1243.07 RON

1243.07 RON

0.00 RON