Leaflet NALIXID 500mg capsules

Indicated for: bacterial urinary tract infections

Route of administration: oral

Substance: nalidixic acid (antibacterial antibiotic)

ATC: J01MB02 (Antiinfectives for systemic use | Quinolone antibacterials | Other quinolones)

Precautions:
Dose adjustment in renal impairment
Dose adjustment in renal impairment

Dose adjustment may be needed in kidney disease.

Anaphylaxis
Anaphylaxis

Risk of severe allergic reaction. Seek urgent medical help if serious symptoms occur.

Colitis / severe diarrhea
Colitis / severe diarrhea

Seek medical advice if severe or persistent diarrhea occurs.

Major drug interactions
Major drug interactions

This medicine may have important interactions with other medicines.

Nalidixic acid is an antibiotic from the quinolone class primarily used to treat urinary tract infections caused by susceptible bacteria. It is effective against certain gram-negative bacteria, such as Escherichia coli, Proteus spp., and Klebsiella spp., but it is not active against gram-positive or anaerobic bacteria.

Nalidixic acid works by inhibiting bacterial DNA synthesis, leading to bacterial destruction. It is typically used for uncomplicated urinary tract infections, but its use has declined in favor of more modern antibiotics due to increased bacterial resistance.

Side effects may include nausea, vomiting, diarrhea, skin rashes, or, in rare cases, neurological reactions such as dizziness or confusion. It is contraindicated in children under 12 years old, pregnant women, and breastfeeding mothers. Patients should strictly follow their doctor’s instructions and complete the treatment to prevent the development of bacterial resistance.

General data about NALIXID 500mg

  • Substance: nalidixic acid
  • Date of latest medicines list: 01-07-2020
  • Product code: W42791002
  • Concentration: 500mg
  • Pharmaceutical form: capsules
  • Quantity: 30
  • Product type: Generic medicine
  • Prescription status: P-RF - Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.