Leaflet N-CALMANT III tablets


Indicated for: cold and flu symptoms

Route of administration: oral

Substance: paracetamol + codeine + caffeine (analgesic and antipyretic + opioid analgesic + xanthine stimulant)

ATC: N02BE51 (Nervous system | Other analgesics and antipyretics | Anilides)

Precautions:
Driving impairment
Driving impairment

This medicine may affect your ability to drive or use machines.

Dizziness / vertigo
Dizziness / vertigo

This medicine may cause dizziness or vertigo.

Dependence / abuse
Dependence / abuse

This medicine may cause dependence or be misused.

Respiratory depression
Respiratory depression

May slow breathing, especially with alcohol or sedatives.

Avoid alcohol
Avoid alcohol

Avoid alcohol during treatment.

Hepatotoxicity
Hepatotoxicity

This medicine may affect the liver.

Major drug interactions
Major drug interactions

This medicine may have important interactions with other medicines.

Breastfeeding warning
Breastfeeding warning

Use during breastfeeding only on medical advice.

Pregnancy warning
Pregnancy warning

Use during pregnancy only on medical advice.

Elderly warning
Elderly warning

Older people may have an increased risk of side effects.

Withdrawal / do not stop abruptly
Withdrawal / do not stop abruptly

Do not stop treatment abruptly without medical advice.

Drowsiness / sedation
Drowsiness / sedation

This medicine may cause drowsiness or reduced alertness.

Paracetamol, codeine, and caffeine are active ingredients used in combination to treat moderate to severe pain, such as headaches, migraines, dental pain, or muscle pain. This combination is effective due to the synergistic effect of the three components, providing fast and long-lasting pain relief.

Paracetamol is an analgesic and antipyretic that reduces pain and fever, being well-tolerated by most patients. Codeine is a mild opioid that acts on the central nervous system to reduce the perception of pain, enhancing the analgesic effect of paracetamol. Caffeine acts as a stimulant and improves the absorption of analgesics, increasing the treatment's efficiency.

Although this combination is effective, its use should be approached with caution. Codeine can cause dependency if used long-term or in high doses. It may also cause drowsiness, dizziness, or constipation. Caffeine may lead to insomnia, agitation, or palpitations, especially in sensitive individuals. It is important not to exceed the recommended dose to avoid adverse effects, including liver toxicity associated with paracetamol.

This combination is available only by prescription, and its use should be supervised by a doctor. Patients should follow the recommended dosage and avoid alcohol consumption during treatment. If the pain persists or worsens, further medical evaluation is necessary.

General data about N-CALMANT III

  • Substance: paracetamol + codeine + caffeine
  • Date of last drug list: 01-07-2015
  • Commercial code: W61658001
  • Pharmaceutical form: tablets
  • Quantity: 20
  • Product type: generic
  • Prescription restrictions: OTC - Over the Counter = medicines that do not require a prescription.

Marketing authorisation

  • Manufacturer: ARENA GROUP S.A. - ROMANIA
  • Holder: ARENA GROUP S.A. - ROMANIA
  • Number: 1992/2001/01
  • Shelf life: 2 years

Pharmaceutical forms available for paracetamol + codeine + caffeine

Concentrations available for paracetamol + codeine + caffeine

  • 500mg/12.8mg/30mg
  • 500mg/8mg/30mg