Indicated for: angina pectoris
Route of administration: oral
Substance: isosorbide mononitrate (nitrate vasodilator)
ATC: C01DA14 (Cardiovascular system | Vasodilators used in cardiac diseases | Organic nitrates)
Isosorbide mononitrate is a medication used for the prevention and treatment of angina pectoris (chest pain caused by reduced blood flow to the heart). It belongs to the class of organic nitrates and works by relaxing and dilating blood vessels, improving blood flow to the heart and reducing its workload. This mechanism helps prevent angina episodes and alleviate symptoms.
Isosorbide mononitrate is primarily used for the prevention of angina pectoris and is not indicated for the treatment of acute angina episodes. It is taken orally, in the form of immediate-release or extended-release tablets, as prescribed by a doctor. The dosage and frequency are adjusted based on the patient's needs.
Common side effects include headaches (especially at the start of treatment), dizziness, low blood pressure (hypotension), and nausea. These symptoms usually decrease as the body adjusts to the medication. Rarely, allergic reactions or severe hypotension may occur.
Patients should avoid alcohol during treatment, as it can enhance the hypotensive effects of the medication. It is also important not to stop the treatment abruptly without medical advice, as this may worsen symptoms.
Isosorbide mononitrate should not be used in combination with medications for erectile dysfunction (such as sildenafil), as the combination can cause a dangerous drop in blood pressure.