Leaflet MIOFILIN 100mg capsules

Indicated for: asthma; chronic obstructive pulmonary disease

Route of administration: oral

Substance: aminophylline (bronchodilator)

ATC: R03DA05 (Respiratory system | Other systemic drugs for obstructive airway diseases | Xanthines)

Aminophylline is a medication primarily used for the treatment of bronchial asthma, chronic bronchitis, and other respiratory conditions involving airway obstruction. It belongs to a class of drugs called methylxanthines and works by relaxing the smooth muscles in the walls of the airways, thereby facilitating breathing. It also has a mild diuretic effect and stimulates the central nervous system.

Aminophylline can be administered orally, intravenously, or as suppositories, depending on the severity of the condition and the patient's response to treatment. The dosage is carefully adjusted, as the drug has a narrow therapeutic window, and plasma levels must be monitored to avoid toxicity.

Common side effects include nausea, vomiting, headaches, insomnia, and palpitations. In rare cases, severe adverse reactions such as cardiac arrhythmias, seizures, or allergic reactions may occur.

Patients taking aminophylline should undergo regular monitoring, particularly for cardiac function and serum drug levels. Additionally, the medication may interact with other drugs, such as antibiotics or anticonvulsants, necessitating dose adjustments. Aminophylline is an effective option for managing obstructive respiratory conditions, but its use requires careful medical supervision.