Leaflet METOPIRONE 250mg soft capsules

Product code:
W71299001
Quantity:
50
Indicated for:
endogenous Cushing syndrome
Route of administration:
oral
Substance:
metirapone (steroidogenesis inhibitor)
ATC
V04CD01 — Various | Other diagnostic agents | Tests for pituitary function
Metyrapone is a cortisol synthesis inhibitor used for the diagnosis of adrenal insufficiency and the treatment of Cushing's syndrome. It works by inhibiting the enzyme 11-beta-hydroxylase, reducing cortisol production.

The medication is taken orally, usually in divided doses, with the dose adjusted based on the patient's response and hormone levels. Common side effects include nausea, vomiting, abdominal pain, and dizziness.

Metyrapone is contraindicated in patients with hypersensitivity to the active substance or severe hepatic impairment. Its use also requires careful monitoring of adrenal function and blood pressure.

This medication is an important option for diagnosing and managing adrenal disorders, helping to improve patients' quality of life.

General data about METOPIRONE 250mg

Substance:
metirapone
Date of latest medicines list:
01-06-2026
Product code:
W71299001
Concentration:
250mg
Pharmaceutical form:
soft capsules
Quantity:
50
Product type:
Generic medicine
Price:
1299.28 RON
Prescription status:
P-RF — Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.

Marketing authorisation

Manufacturer:
DELPHARM LILLE S.A.S. - FRANTA
Holder:
ESTEVE PHARMACEUTICALS S.A. - SPANIA
Number:
15076/2023/01
Shelf life:
3 years-after packing for marketing;after the first opening of the bottle-2 months