Indicated for: Alzheimer's disease; dementia
Route of administration: oral
Substance: memantine (NMDA receptor antagonist)
ATC: N06DX01 (Nervous system | Anti-dementia drugs | Other anti-dementia drugs)
Memantine is a medication used to treat moderate to severe dementia associated with Alzheimer’s disease. It works by blocking NMDA (N-methyl-D-aspartate) receptors in the brain, reducing the excessive effects of glutamate, a neurotransmitter that, in high amounts, can contribute to nerve cell damage.
Memantine helps improve cognitive function, memory, and the ability to perform daily activities, but it does not cure Alzheimer’s disease. It is usually administered in tablet or oral solution form, with the dose gradually adjusted to minimize side effects.
Side effects may include dizziness, headaches, constipation, drowsiness, or confusion. In rare cases, hallucinations or high blood pressure may occur. It is important to take the medication as prescribed by a doctor, with regular monitoring of the patient’s condition.