Leaflet MELFALAN ZENTIVA 50mg powder and solvent for solution for injection / infusion

Product code:
W68577001
Quantity:
1
Indicated for:
cancer
Route of administration:
injectable / infusion
Substance:
melphalan (alkylating antineoplastic agent)
ATC
L01AA03 — Antineoplastic and immunomodulating agents | Alkylating agents | Nitrogen mustard analogues

Precautions:

Fertility warning

Fertility warning

This medicine may affect fertility.

Dose adjustment in hepatic impairment

Dose adjustment in hepatic impairment

Dose adjustment may be needed in liver disease.

Cytotoxic / special handling

Cytotoxic / special handling

Handle with special care.

Contraception required

Contraception required

Effective contraception is required during treatment.

Contraindicated during breastfeeding

Contraindicated during breastfeeding

Do not use this medicine while breastfeeding.

Contraindicated during pregnancy

Contraindicated during pregnancy

Do not use this medicine during pregnancy.

Hepatotoxicity

Hepatotoxicity

This medicine may affect the liver.

Major drug interactions

Major drug interactions

This medicine may have important interactions with other medicines.

Myelosuppression / agranulocytosis

Myelosuppression / agranulocytosis

This medicine may lower blood cell counts.

Additional monitoring

Additional monitoring

This medicine is subject to additional monitoring.

Requires periodic laboratory tests

Requires periodic laboratory tests

Periodic laboratory tests may be required during treatment.

Severe skin reactions

Severe skin reactions

Stop taking the medicine and seek urgent medical help if a severe rash occurs.

Melphalan is a chemotherapy agent primarily used to treat certain types of cancer, such as multiple myeloma and ovarian cancer. It works by interfering with the DNA of cancer cells, preventing them from dividing and spreading.

Melphalan is administered either orally or intravenously, depending on the type and stage of cancer being treated. The treatment may be associated with side effects such as nausea, vomiting, decreased blood cell counts, and an increased risk of infections.

Patients undergoing melphalan treatment must be closely monitored by their doctor to assess effectiveness and manage any adverse reactions. It is important to strictly follow the prescribed doses.

This medication is used only under strict medical supervision and is not recommended for pregnant or breastfeeding women due to risks to the fetus or child.

General data about MELFALAN ZENTIVA 50mg

Substance:
melphalan
Date of latest medicines list:
01-06-2026
Product code:
W68577001
Concentration:
50mg
Pharmaceutical form:
powder and solvent for solution for injection / infusion
Quantity:
1
Product type:
Generic medicine
Price:
900.51 RON
Prescription status:
P-RF — Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.

Marketing authorisation

Manufacturer:
MIAS PHARMA LIMITED - IRLANDA
Holder:
ZENTIVA K.S. - REPUBLICA CEHA
Number:
15272/2024/01
Shelf life:
2 years; After first opening the bottle. - it is used immediately

Concentrations available for melphalan

  • 200mg
  • 2mg
  • 50mg

Compensation lists for MELFALAN ZENTIVA 50mg Zentiva

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Copayment
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