Indicated for: bleeding; coagulation disorders
Route of administration: injectable
Substance: tranexamic acid (antifibrinolytic)
ATC: B02AA02 (Blood and blood forming organs | Antifibrinolytics | Amino acids)
Tranexamic acid is an antifibrinolytic agent used to prevent and treat excessive bleeding caused by increased fibrinolysis, a process in which blood clots dissolve too quickly. It works by inhibiting plasminogen, thereby reducing fibrin degradation and helping to stabilize blood clots.
It is used for the treatment of heavy menstrual bleeding (menorrhagia), postoperative hemorrhages, severe trauma, and hemophilia. It is also administered in postpartum hemorrhage to reduce the risk of severe complications.
Tranexamic acid can be given orally, intravenously, or topically, depending on the medical indication. It is preferred for its relatively high safety profile and effectiveness in reducing blood loss without significantly increasing the risk of thrombosis.
Side effects include nausea, diarrhea, headache, and, in rare cases, severe allergic reactions or thrombotic events. It is not recommended for patients with a history of thromboembolism without close medical supervision.