Indicated for: vitamin D deficiency; calcium metabolism disorders
Route of administration: oral
Substance: alfacalcidol (vitamin D / vitamin D analogue)
ATC: A11CC03 (Alimentary tract and metabolism | Vitamin A and D, including combinations of the two | Vitamin D and analogues)
Alfacalcidol is an active derivative of vitamin D used to treat and prevent disorders related to calcium and phosphorus metabolism. It is indicated for conditions such as renal osteodystrophy, hypoparathyroidism, rickets, and osteomalacia, particularly in patients with chronic kidney disease.
Alfacalcidol works by increasing the absorption of calcium and phosphorus from the intestine and regulating their levels in the blood, thereby supporting bone health and muscle function. It is administered orally or intravenously, depending on the indication.
Side effects may include hypercalcemia (elevated calcium levels in the blood), which can manifest as nausea, vomiting, excessive thirst, frequent urination, or muscle weakness. Regular monitoring of calcium and phosphorus levels is essential during treatment. The medication should be taken as prescribed by a doctor, and patients should avoid calcium or vitamin D supplements without medical advice.