Leaflet MADOPAR DEPOT 100mg / 25mg modified release capsules

Indicated for: Parkinson's disease

Route of administration: oral

Substance: levodopa + benserazide (antiparkinsonian agents)

ATC: N04BA02 (Nervous system | Dopaminergic agents | Dopa and dopa derivatives)

Precautions:
Driving impairment
Driving impairment

This medicine may affect your ability to drive or use machines.

Dizziness / vertigo
Dizziness / vertigo

This medicine may cause dizziness or vertigo.

Hypotension / fall risk
Hypotension / fall risk

May lower blood pressure and increase the risk of falls.

Drowsiness / sedation
Drowsiness / sedation

This medicine may cause drowsiness or reduced alertness.

Levodopa + Benserazide is a combination medication used in the treatment of Parkinson's disease and parkinsonian syndromes. Levodopa is a precursor of dopamine, which helps compensate for the dopamine deficiency in the brain characteristic of these conditions. Benserazide is a peripheral decarboxylase inhibitor that prevents levodopa from being converted into dopamine outside the brain, thereby increasing the treatment's effectiveness and reducing side effects.

This combination helps alleviate symptoms such as tremors, muscle rigidity, bradykinesia (slowness of movement), and balance difficulties. It is important to take the medication as prescribed by a doctor, with the dosage gradually adjusted to minimize side effects.

Side effects may include nausea, vomiting, dizziness, drowsiness, or motor fluctuations (such as 'on-off' phenomena). In rare cases, hallucinations or mood changes may occur. Regular medical monitoring is essential to adjust the treatment based on the progression of the disease.

General data about MADOPAR DEPOT 100mg / 25mg

  • Substance: levodopa + benserazide
  • Date of latest medicines list: 01-06-2026
  • Product code: W69929003
  • Concentration: 100mg / 25mg
  • Pharmaceutical form: modified release capsules
  • Quantity: 100
  • Product type: Generic medicine
  • Price: 66.30 RON
  • Prescription status: P-6L - Medicines dispensed with a medical prescription that is not retained by the pharmacy and may be renewed; the prescription may be used for 6 months from the date of issue.

Marketing authorisation

  • Manufacturer: ROCHE PHARMA AG - GERMANIA
  • Holder: ROCHE ROMANIA S.R.L. - ROMANIA
  • Number: 7/2023/03
  • Shelf life: 3 years

Pharmaceutical forms available for levodopa + benserazide

Concentrations available for levodopa + benserazide

  • 100mg/25mg
  • 200mg/50mg

Compensation lists for MADOPAR DEPOT 100mg / 25mg Roche

G12 (C1) - Parkinson's disease

Price

Copayment

Patient

66.30 RON

66.30 RON

0.00 RON

GX (C1) - GENERIC (used in compensation list, C1, for another diagnosis)

Price

Copayment

Patient

66.30 RON

66.30 RON

0.00 RON