MADOPAR DEPOT 100mg / 25mg modified release capsules medication leaflet

N04BA02 • levodopa + benserazide • Nervous system | Dopaminergic agents | Dopa and dopa derivatives

Levodopa + Benserazide is a combination medication used in the treatment of Parkinson's disease and parkinsonian syndromes. Levodopa is a precursor of dopamine, which helps compensate for the dopamine deficiency in the brain characteristic of these conditions. Benserazide is a peripheral decarboxylase inhibitor that prevents levodopa from being converted into dopamine outside the brain, thereby increasing the treatment's effectiveness and reducing side effects.

This combination helps alleviate symptoms such as tremors, muscle rigidity, bradykinesia (slowness of movement), and balance difficulties. It is important to take the medication as prescribed by a doctor, with the dosage gradually adjusted to minimize side effects.

Side effects may include nausea, vomiting, dizziness, drowsiness, or motor fluctuations (such as 'on-off' phenomena). In rare cases, hallucinations or mood changes may occur. Regular medical monitoring is essential to adjust the treatment based on the progression of the disease.