Leaflet LODOZ 2.5mg / 6.25mg film-coated tablets


Indicated for: hypertension

Route of administration: oral

Substance: bisoprolol + hydrochlorothiazide (beta blocker + diuretic)

ATC: C07BB07 (Cardiovascular system | Beta blocking agents and thiazides | Beta blocking agents, selective, and thiazides)

Precautions:
Dose adjustment in renal impairment
Dose adjustment in renal impairment

Dose adjustment may be needed in kidney disease.

Dizziness / vertigo
Dizziness / vertigo

This medicine may cause dizziness or vertigo.

Photosensitivity
Photosensitivity

Avoid excessive exposure to sunlight or UV radiation.

Hypotension / fall risk
Hypotension / fall risk

May lower blood pressure and increase the risk of falls.

Requires periodic laboratory tests
Requires periodic laboratory tests

Periodic laboratory tests may be required during treatment.

Elderly warning
Elderly warning

Older people may have an increased risk of side effects.

Electrolyte disturbances
Electrolyte disturbances

This medicine may change blood electrolyte levels.

The combination of bisoprolol and hydrochlorothiazide is used to treat hypertension. Bisoprolol is a beta-blocker that reduces heart rate and blood pressure, while hydrochlorothiazide is a diuretic that helps eliminate excess water and salt from the body, thereby reducing blood volume.

The medication is taken orally, usually once daily, as directed by a doctor. It is important for patients to follow the prescribed dosage and not discontinue treatment without consulting their doctor.

Common side effects include dizziness, fatigue, nausea, and dry mouth. In rare cases, more severe adverse effects such as excessive blood pressure reduction, electrolyte imbalances, or allergic reactions may occur.

This combination is not recommended for pregnant or breastfeeding women unless the benefits outweigh the risks. Patients with severe kidney failure or other chronic conditions should consult their doctor before starting treatment.

General data about LODOZ 2.5mg / 6.25mg

  • Substance: bisoprolol + hydrochlorothiazide
  • Date of last drug list: 01-06-2026
  • Commercial code: W57345003
  • Concentration: 2.5mg / 6.25mg
  • Pharmaceutical form: film-coated tablets
  • Quantity: 30
  • Product type: original
  • Price: 18.85 RON
  • Prescription restrictions: P-6L - Medicines prescription that isn't retained in the pharmacy (can be renewed); the prescription can be used for 6 months from the moment of release.

Marketing authorisation

  • Manufacturer: MERCK HEALTHCARE KGAA - GERMANIA
  • Holder: MERCK ROMANIA SRL - ROMANIA
  • Number: 9841/2017/01
  • Shelf life: 5 years

Concentrations available for bisoprolol + hydrochlorothiazide

  • 10mg/6.25mg
  • 2.5mg/6.25mg
  • 5mg/6.25mg