Leaflet LIPERTANCE 40mg / 10mg / 10mg film-coated tablets

Product code:
W62546004
Quantity:
28
Indicated for:
dyslipidemia; hypertension
Route of administration:
oral
Substance:
atorvastatin + perindopril + amlodipine (statin lipid-lowering agent + ACE inhibitor + calcium channel blocker)
ATC
C10BX11 — Cardiovascular system | Lipid modifying agents | Lipid modifying agents, combinations | Lipid modifying agents in combination with other drugs

Precautions:

Contraindicated during pregnancy

Do not use this medicine during pregnancy.

Avoid grapefruit

Avoid grapefruit and grapefruit juice.

Hepatotoxicity

This medicine may affect the liver.

Hypotension / fall risk

May lower blood pressure and increase the risk of falls.

Major drug interactions

This medicine may have important interactions with other medicines.

Myopathy / rhabdomyolysis

Seek medical advice if unexplained muscle pain occurs.

Requires periodic laboratory tests

Periodic laboratory tests may be required during treatment.

Electrolyte disturbances

This medicine may change blood electrolyte levels.

The combination of atorvastatin, perindopril, and amlodipine is used for the treatment of patients at high cardiovascular risk who require simultaneous management of dyslipidemia, hypertension, and other cardiovascular risk factors. Atorvastatin lowers LDL cholesterol levels, perindopril is an angiotensin-converting enzyme (ACE) inhibitor that reduces blood pressure and protects the heart, and amlodipine is a calcium channel blocker that relaxes blood vessels.

This combination is administered orally, usually once daily, with the dosage adjusted based on the patient's needs and response to treatment. It is particularly indicated for patients with stable cardiovascular disease or multiple comorbidities.

Common side effects include dizziness, headaches, peripheral edema, dry cough, and muscle pain. In rare cases, severe adverse reactions such as renal failure, rhabdomyolysis, or allergic reactions may occur.

Patients taking this combination should undergo regular monitoring for liver and kidney function, lipid levels, and blood pressure. The atorvastatin, perindopril, and amlodipine combination provides a comprehensive solution for managing overall cardiovascular risk, helping to prevent major cardiovascular events.

General data about LIPERTANCE 40mg / 10mg / 10mg

Substance:
atorvastatin + perindopril + amlodipine
Date of latest medicines list:
01-12-2020
Product code:
W62546004
Concentration:
40mg / 10mg / 10mg
Pharmaceutical form:
film-coated tablets
Quantity:
28
Product type:
Generic medicine
Prescription status:
P-6L — Medicines dispensed with a medical prescription that is not retained by the pharmacy and may be renewed; the prescription may be used for 6 months from the date of issue.

Marketing authorisation

Manufacturer:
LES LABORATOIRES SERVIER INDUSTRIE - FRANTA
Holder:
LES LABORATOIRES SERVIER - FRANTA
Number:
13332/2020/01
Shelf life:
2 years

Concentrations available for atorvastatin + perindopril + amlodipine

  • 10mg/5mg/5mg
  • 20mg/10mg/10mg
  • 20mg/10mg/5mg
  • 20mg/5mg/5mg
  • 40mg/10mg/10mg