Leaflet LIPERTANCE 40mg / 10mg / 10mg film-coated tablets

Indicated for: dyslipidemia; hypertension

Route of administration: oral

Substance: atorvastatin + perindopril + amlodipine (statin lipid-lowering agent + ACE inhibitor + calcium channel blocker)

ATC: C10BX11 (Cardiovascular system | Lipid modifying agents, combinations | Lipid modifying agents in combination with other drugs)

Precautions:
Contraindicated during pregnancy
Contraindicated during pregnancy

Do not use this medicine during pregnancy.

Avoid grapefruit
Avoid grapefruit

Avoid grapefruit and grapefruit juice.

Hepatotoxicity
Hepatotoxicity

This medicine may affect the liver.

Hypotension / fall risk
Hypotension / fall risk

May lower blood pressure and increase the risk of falls.

Major drug interactions
Major drug interactions

This medicine may have important interactions with other medicines.

Myopathy / rhabdomyolysis
Myopathy / rhabdomyolysis

Seek medical advice if unexplained muscle pain occurs.

Requires periodic laboratory tests
Requires periodic laboratory tests

Periodic laboratory tests may be required during treatment.

Electrolyte disturbances
Electrolyte disturbances

This medicine may change blood electrolyte levels.

The combination of atorvastatin, perindopril, and amlodipine is used for the treatment of patients at high cardiovascular risk who require simultaneous management of dyslipidemia, hypertension, and other cardiovascular risk factors. Atorvastatin lowers LDL cholesterol levels, perindopril is an angiotensin-converting enzyme (ACE) inhibitor that reduces blood pressure and protects the heart, and amlodipine is a calcium channel blocker that relaxes blood vessels.

This combination is administered orally, usually once daily, with the dosage adjusted based on the patient's needs and response to treatment. It is particularly indicated for patients with stable cardiovascular disease or multiple comorbidities.

Common side effects include dizziness, headaches, peripheral edema, dry cough, and muscle pain. In rare cases, severe adverse reactions such as renal failure, rhabdomyolysis, or allergic reactions may occur.

Patients taking this combination should undergo regular monitoring for liver and kidney function, lipid levels, and blood pressure. The atorvastatin, perindopril, and amlodipine combination provides a comprehensive solution for managing overall cardiovascular risk, helping to prevent major cardiovascular events.

General data about LIPERTANCE 40mg / 10mg / 10mg

  • Substance: atorvastatin + perindopril + amlodipine
  • Date of latest medicines list: 01-12-2020
  • Product code: W62546004
  • Concentration: 40mg / 10mg / 10mg
  • Pharmaceutical form: film-coated tablets
  • Quantity: 28
  • Product type: Generic medicine
  • Prescription status: P-6L - Medicines dispensed with a medical prescription that is not retained by the pharmacy and may be renewed; the prescription may be used for 6 months from the date of issue.

Marketing authorisation

  • Manufacturer: LES LABORATOIRES SERVIER INDUSTRIE - FRANTA
  • Holder: LES LABORATOIRES SERVIER - FRANTA
  • Number: 13332/2020/01
  • Shelf life: 2 years

Concentrations available for atorvastatin + perindopril + amlodipine

  • 10mg/5mg/5mg
  • 20mg/10mg/10mg
  • 20mg/10mg/5mg
  • 20mg/5mg/5mg
  • 40mg/10mg/10mg