Leaflet LEUKERAN 2mg film-coated tablets
Indicated for: hematologic malignancies
Route of administration: oral
Substance: chlorambucil (alkylating antineoplastic agent)
ATC: L01AA02 (Antineoplastic and immunomodulating agents | Alkylating agents | Nitrogen mustard analogues)
This medicine may affect fertility.
Dose adjustment may be needed in liver disease.
Handle with special care.
Effective contraception is required during treatment.
Do not use this medicine while breastfeeding.
Do not use this medicine during pregnancy.
This medicine may affect the liver.
This medicine may have important interactions with other medicines.
This medicine may lower blood cell counts.
This medicine is subject to additional monitoring.
Periodic laboratory tests may be required during treatment.
Stop taking the medicine and seek urgent medical help if a severe rash occurs.
Chlorambucil is an alkylating agent used in the treatment of certain types of cancer, including Hodgkin's lymphoma, non-Hodgkin's lymphoma, and chronic lymphocytic leukemia. It works by interfering with the DNA of cancer cells, thereby inhibiting their growth and division.
The medication is taken orally, usually once daily, and the dosage is adjusted based on the patient's weight and response to treatment. Chlorambucil is primarily used as part of a chemotherapy regimen.
Patients should be closely monitored to detect potential side effects, such as bone marrow suppression, nausea, vomiting, or skin rashes. It is important for patients to inform their doctor of any unusual symptoms.
Common side effects include fatigue, nausea, decreased blood cell counts, and skin rashes. In rare cases, severe reactions such as liver toxicity or an increased risk of infections may occur. Patients should be informed of these risks before starting treatment.
General data about LEUKERAN 2mg
- Substance: chlorambucil
- Date of latest medicines list: 01-06-2026
- Product code: W58866002
- Concentration: 2mg
- Pharmaceutical form: film-coated tablets
- Quantity: 25
- Product type: Original
- Price: 73.39 RON
- Prescription status: P-RF - Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.