Leaflet LEUJECT 2mg / ml solution for injection


Indicated for: multiple sclerosis; chronic lymphocytic leukemia

Route of administration: injectable

Substance: cladribine (antimetabolite antineoplastic)

ATC: L01BB04 (Antineoplastic and immunomodulating agents | Antimetabolites | Purine analogues)

Precautions:
Fertility warning
Fertility warning

This medicine may affect fertility.

Dose adjustment in hepatic impairment
Dose adjustment in hepatic impairment

Dose adjustment may be needed in liver disease.

Cytotoxic / special handling
Cytotoxic / special handling

Handle with special care.

Contraception required
Contraception required

Effective contraception is required during treatment.

Contraindicated during breastfeeding
Contraindicated during breastfeeding

Do not use this medicine while breastfeeding.

Contraindicated during pregnancy
Contraindicated during pregnancy

Do not use this medicine during pregnancy.

Hepatotoxicity
Hepatotoxicity

This medicine may affect the liver.

Major drug interactions
Major drug interactions

This medicine may have important interactions with other medicines.

Myelosuppression / agranulocytosis
Myelosuppression / agranulocytosis

This medicine may lower blood cell counts.

Additional monitoring
Additional monitoring

This medicine is subject to additional monitoring.

Requires periodic laboratory tests
Requires periodic laboratory tests

Periodic laboratory tests may be required during treatment.

Severe skin reactions
Severe skin reactions

Stop taking the medicine and seek urgent medical help if a severe rash occurs.

Cladribine is a medication used to treat hairy cell leukemia and relapsing multiple sclerosis. It works by inhibiting DNA synthesis in rapidly dividing cells, such as cancer cells or overactive immune cells.

The medication is administered either as injections or tablets, depending on the therapeutic indication. It is important to use it as prescribed by your doctor to achieve the best results.

Side effects may include nausea, fatigue, fever, decreased blood cell counts, and an increased risk of infections. In rare cases, severe allergic reactions or other complications may occur, requiring immediate medical attention.

Patients should inform their doctor about any other medications being used or pre-existing conditions, such as active infections or liver diseases, as these may affect the safety of cladribine use.

General data about LEUJECT 2mg / ml

  • Substance: cladribine
  • Date of last drug list: 01-04-2025
  • Commercial code: W70932001
  • Concentration: 2mg / ml
  • Pharmaceutical form: solution for injection
  • Quantity: 1
  • Product type: generic
  • Prescription restrictions: P-RF - Medicines prescription that is retained in the pharmacy (not renewable).

Marketing authorisation

  • Manufacturer: PHARMA PACK HUNGARY KFT. - UNGARIA
  • Holder: ATNAHS PHARMA NETHERLANDS B.V. - DANEMARCA
  • Number: 15837/2025/01
  • Shelf life: 4 years

Pharmaceutical forms available for cladribine

Concentrations available for cladribine

  • 10mg
  • 2mg/ml