Leaflet KOMBOGLYZE 2.5mg/1000mg 2.5 / 1000mg film-coated tablets

Indicated for: type 2 diabetes mellitus

Route of administration: oral

Substance: saxagliptin + metformin (DPP-4 inhibitor + biguanide antidiabetic)

ATC: A10BD10 (Alimentary tract and metabolism | Blood glucose lowering drugs, excl. insulins | Combinations of oral blood glucose lowering drugs)

Precautions:
Dose adjustment in renal impairment
Dose adjustment in renal impairment

Dose adjustment may be needed in kidney disease.

Requires periodic laboratory tests
Requires periodic laboratory tests

Periodic laboratory tests may be required during treatment.

Saxagliptin+metformin is a combination medication used in the treatment of type 2 diabetes mellitus. Saxagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that increases levels of active incretins, stimulating insulin secretion and reducing glucagon production. Metformin, a biguanide, reduces hepatic glucose production and improves glucose utilization by tissues.

This combination is taken orally, usually twice daily, and is indicated for patients who fail to control their blood sugar levels through diet, exercise, or monotherapy. It is effective in reducing glycated hemoglobin (HbA1c) levels and preventing diabetes-related complications.

Common side effects include nausea, diarrhea, upper respiratory tract infections, and headache. In rare cases, severe adverse reactions such as pancreatitis or lactic acidosis may occur. Regular monitoring of renal function and blood glucose levels is essential.

Saxagliptin+metformin is a valuable therapeutic option for patients with type 2 diabetes, offering improved glycemic control through complementary mechanisms of action.

General data about KOMBOGLYZE 2.5mg/1000mg 2.5 / 1000mg

  • Substance: saxagliptin + metformin
  • Date of latest medicines list: 01-06-2016
  • Product code: W58716001
  • Concentration: 2.5 / 1000mg
  • Pharmaceutical form: film-coated tablets
  • Quantity: 28
  • Product type: Original
  • Prescription status: P-RF - Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.

Concentrations available for saxagliptin + metformin

  • 2.5/1000mg
  • 2.5/850mg
  • 2.5mg/1000mg
  • 2.5mg/850mg

Other substances similar to saxagliptin + metformin