Avoid grapefruit
Avoid grapefruit and grapefruit juice.
Leaflet KALETRA 133.3mg / 33.3mg soft capsules
- Product code:
- W59949001
- Quantity:
- 180
- Indicated for:
- HIV-1 infection
- Route of administration:
- oral
- Substance:
- lopinavir + ritonavir (protease inhibitors)
- ATC
- J05AE06 — Antiinfectives for systemic use | Direct acting antivirals | Protease inhibitors
Precautions:
Breastfeeding warning
Use during breastfeeding only on medical advice.
Pregnancy warning
Use during pregnancy only on medical advice.
Lopinavir + ritonavir is a combination medication used for the treatment of human immunodeficiency virus (HIV) infection. It belongs to the class of protease inhibitors and is used to reduce the viral load in the body, helping to delay disease progression and maintain immune system function.
- Lopinavir is the main active agent that inhibits HIV protease, an enzyme essential for viral replication.
- Ritonavir is used in low doses to boost lopinavir levels in the blood by inhibiting its metabolism in the liver (boosting effect).
This combination is administered as tablets or oral solution, usually twice daily, in combination with other antiretroviral drugs as part of highly active antiretroviral therapy (HAART).
Side effects may include nausea, diarrhea, abdominal pain, fatigue, increased cholesterol and triglyceride levels, and changes in liver function. In rare cases, it may cause pancreatitis or severe allergic reactions. It is important to take the medication as prescribed by a doctor, and patients should be regularly monitored to assess treatment effectiveness and prevent adverse effects.
- Lopinavir is the main active agent that inhibits HIV protease, an enzyme essential for viral replication.
- Ritonavir is used in low doses to boost lopinavir levels in the blood by inhibiting its metabolism in the liver (boosting effect).
This combination is administered as tablets or oral solution, usually twice daily, in combination with other antiretroviral drugs as part of highly active antiretroviral therapy (HAART).
Side effects may include nausea, diarrhea, abdominal pain, fatigue, increased cholesterol and triglyceride levels, and changes in liver function. In rare cases, it may cause pancreatitis or severe allergic reactions. It is important to take the medication as prescribed by a doctor, and patients should be regularly monitored to assess treatment effectiveness and prevent adverse effects.
General data about KALETRA 133.3mg / 33.3mg
- Substance:
- lopinavir + ritonavir
- Date of latest medicines list:
- 02-10-2013
- Product code:
- W59949001
- Concentration:
- 133.3mg / 33.3mg
- Pharmaceutical form:
- soft capsules
- Quantity:
- 180
- Product type:
- Original
- Prescription status:
- P-RF — Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.
Pharmaceutical forms available for lopinavir + ritonavir
Concentrations available for lopinavir + ritonavir
- 100mg/25mg
- 133.3mg/33.3mg
- 200mg/50mg
- 80mg/20mg/ml