Leaflet JAVLOR 25mg / ml concentrate for solution for infusion
Indicated for: cancer
Route of administration: infusion
Substance: vinflunine (antineoplastic agent)
ATC: L01CA05 (Antineoplastic and immunomodulating agents | Plant alkaloids and other natural products | Vinca alkaloids and analogues)
This medicine may affect fertility.
Dose adjustment may be needed in liver disease.
Handle with special care.
Effective contraception is required during treatment.
Do not use this medicine while breastfeeding.
Do not use this medicine during pregnancy.
This medicine may affect the liver.
This medicine may have important interactions with other medicines.
This medicine may lower blood cell counts.
This medicine is subject to additional monitoring.
Periodic laboratory tests may be required during treatment.
Stop taking the medicine and seek urgent medical help if a severe rash occurs.
Vinflunine is a chemotherapy medication primarily used for the treatment of advanced or metastatic urothelial cancer, particularly in patients who have not responded to other platinum-based therapies. It belongs to the vinca alkaloid class and works by inhibiting tubulin polymerization, leading to the arrest of cell division and ultimately tumor cell death.
Vinflunine is administered intravenously, usually once every three weeks, and the dosage is adjusted based on body weight and the patient's overall condition. Treatment is conducted under the supervision of an oncologist, and patients are monitored for signs of toxicity.
Common side effects include fatigue, nausea, vomiting, constipation, anemia, and neutropenia. In rare cases, severe adverse reactions such as peripheral neuropathy or liver function impairment may occur.
Vinflunine represents an important option for patients with advanced urothelial cancer, offering a chance to control disease progression and improve their quality of life.
General data about JAVLOR 25mg / ml
- Substance: vinflunine
- Date of latest medicines list: 01-04-2015
- Product code: W54695005
- Concentration: 25mg / ml
- Pharmaceutical form: concentrate for solution for infusion
- Quantity: 1
- Product type: Original
- Prescription status: P-RF - Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.