Indicated for: HIV-1 infection
Substance: saquinavir (protease inhibitor)
ATC: J05AE01 (Antiinfectives for systemic use | Direct acting antivirals | Protease inhibitors)
Saquinavir is a protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection. It works by inhibiting the HIV protease enzyme, which is essential for processing viral proteins and forming mature viral particles, thereby reducing viral replication in the body.
Saquinavir is administered orally, usually in combination with other antiretroviral medications, as part of highly active antiretroviral therapy (HAART). It is used to reduce viral load, increase CD4 cell counts, and prevent the progression of the disease to acquired immunodeficiency syndrome (AIDS).
Common side effects include nausea, diarrhea, abdominal pain, and fatigue. In rare cases, severe adverse reactions such as hepatotoxicity, hyperglycemia, or allergic reactions may occur. Regular monitoring of liver function and metabolic parameters is essential.
Saquinavir is an important component of antiretroviral therapy, contributing to the effective management of HIV infection and improving patients' quality of life.