Leaflet IMAKREBIN 100mg film-coated tablets

Product code:
W59486006
Quantity:
120
Indicated for:
chronic myeloid leukemia; gastrointestinal stromal tumors
Route of administration:
oral
Substance:
imatinib (tyrosine kinase inhibitor)
ATC
L01EA01 — Antineoplastic and immunomodulating agents | Protein kinase inhibitors | BCR-ABL tyrosine kinase inhibitors

Precautions:

Fertility warning

Fertility warning

This medicine may affect fertility.

Cytotoxic / special handling

Cytotoxic / special handling

Handle with special care.

Contraception required

Contraception required

Effective contraception is required during treatment.

Contraindicated during breastfeeding

Contraindicated during breastfeeding

Do not use this medicine while breastfeeding.

Contraindicated during pregnancy

Contraindicated during pregnancy

Do not use this medicine during pregnancy.

Avoid grapefruit

Avoid grapefruit

Avoid grapefruit and grapefruit juice.

Hepatotoxicity

Hepatotoxicity

This medicine may affect the liver.

Major drug interactions

Major drug interactions

This medicine may have important interactions with other medicines.

Myelosuppression / agranulocytosis

Myelosuppression / agranulocytosis

This medicine may lower blood cell counts.

Additional monitoring

Additional monitoring

This medicine is subject to additional monitoring.

Requires periodic laboratory tests

Requires periodic laboratory tests

Periodic laboratory tests may be required during treatment.

Severe skin reactions

Severe skin reactions

Stop taking the medicine and seek urgent medical help if a severe rash occurs.

Cardiac risk / QT prolongation / arrhythmias

Cardiac risk / QT prolongation / arrhythmias

This medicine may increase the risk of heart rhythm disturbances.

Imatinib is a tyrosine kinase inhibitor used for the treatment of chronic myeloid leukemia (CML) and other cancers, such as gastrointestinal stromal tumors (GIST). It works by blocking the activity of abnormal proteins that drive cancer cell growth.

The medication is taken orally, usually once daily, as directed by a doctor. It is important to follow the recommended dose to maximize treatment effectiveness.

Side effects may include nausea, vomiting, fluid retention, muscle pain, or fatigue. In rare cases, severe allergic reactions or liver failure may occur.

Imatinib is not recommended for patients with hypersensitivity to this medication or severe liver impairment.

General data about IMAKREBIN 100mg

Substance:
imatinib
Date of latest medicines list:
01-06-2026
Product code:
W59486006
Concentration:
100mg
Pharmaceutical form:
film-coated tablets
Quantity:
120
Product type:
Generic medicine
Price:
807.62 RON
Prescription status:
P-RF — Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.

Marketing authorisation

Manufacturer:
REMEDICA LTD. - CIPRU
Holder:
ALVOGEN IPCO S.AR.L. - LUXEMBURG
Number:
11411/2019/06
Shelf life:
3 years

Pharmaceutical forms available for imatinib

Concentrations available for imatinib

  • 100mg
  • 300mg
  • 400mg
  • 50mg

Compensation lists for IMAKREBIN 100mg Alvogen

NHP 3 (C2) - NHP oncology

Price
807.62 RON
Copayment
807.62 RON
Patient
0.00 RON