Leaflet IBUVALEN DUO 200mg / 12.8mg film-coated tablets
Indicated for: pain and inflammation
Route of administration: oral
Substance: ibuprofen + codeine (nonsteroidal anti-inflammatory drug + opioid analgesic)
ATC: M01AE51 (Musculo-skeletal system | Antiinflammatory and antirheumatic products, non-steroids | Propionic acid derivatives)
This medicine may affect your ability to drive or use machines.
This medicine may cause dizziness or vertigo.
This medicine may cause dependence or be misused.
May slow breathing, especially with alcohol or sedatives.
Avoid alcohol during treatment.
This medicine may have important interactions with other medicines.
This medicine may affect the kidneys.
Use during breastfeeding only on medical advice.
Use during pregnancy only on medical advice.
Older people may have an increased risk of side effects.
This medicine may increase the risk of bleeding.
Do not stop treatment abruptly without medical advice.
This medicine may cause drowsiness or reduced alertness.
This medicine may increase the risk of ulcer or gastrointestinal bleeding.
Ibuprofen and codeine are active ingredients used in combination to treat moderate to severe pain, such as headaches, dental pain, muscle pain, postoperative pain, or pain associated with inflammatory conditions. This combination is effective due to the synergistic effect of the two components, providing fast and long-lasting pain relief.
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation, pain, and fever by inhibiting the synthesis of prostaglandins, substances involved in the inflammatory process. Codeine is a mild opioid that acts on the central nervous system to reduce the perception of pain, enhancing the analgesic effect of ibuprofen.
Although this combination is effective, its use should be approached with caution. Codeine can cause dependency if used long-term or in high doses. It may also cause drowsiness, dizziness, constipation, or nausea. Ibuprofen may cause gastrointestinal side effects, such as stomach irritation, heartburn, or ulcers, especially with long-term use. It is important not to exceed the recommended dose.
This combination is available only by prescription, and its use should be supervised by a doctor. Patients should follow the recommended dosage and avoid alcohol consumption during treatment. If pain persists or worsens, further medical evaluation is necessary.
General data about IBUVALEN DUO 200mg / 12.8mg
- Substance: ibuprofen + codeine
- Date of latest medicines list: 01-04-2026
- Product code: W62165002
- Concentration: 200mg / 12.8mg
- Pharmaceutical form: film-coated tablets
- Quantity: 10
- Product type: Generic medicine
- Prescription status: OTC - Over the Counter = medicine that does not require a medical prescription.
Concentrations available for ibuprofen + codeine
- 200mg+12.80mg
- 200mg/12.8mg
- 400mg/30mg