IBUTIN 300mg prolonged tablets medication leaflet

A03AA05 trimebutin • Alimentary tract and metabolism | Drugs for functional gastrointestinal disorders | Synthetic anticholinergics, esters with tertiary amino group

Trimebutine is a medication used to treat functional disorders of the gastrointestinal tract, such as irritable bowel syndrome (IBS), functional dyspepsia, or other conditions associated with spasms and abdominal discomfort. It is a regulator of intestinal motility, capable of normalizing the activity of smooth muscles in the digestive tract.

Trimebutine works by modulating opioid receptors in the intestinal wall, providing a dual effect: it stimulates intestinal motility when it is reduced and inhibits it when it is excessive. This helps alleviate symptoms such as abdominal pain, bloating, constipation, or diarrhea.

The medication is available in the form of tablets, capsules, or oral suspensions and is usually taken 2-3 times a day before meals. The exact dosage and duration of treatment are determined by the doctor, depending on the severity of symptoms and the patient’s response to therapy.

Trimebutine is generally well-tolerated, but mild side effects such as nausea, dry mouth, dizziness, or allergic reactions may occur. In rare cases, more severe adverse effects may develop, requiring discontinuation of the treatment and medical consultation.

This medication is not recommended for young children, pregnant women, or breastfeeding mothers unless strictly necessary and under medical supervision. It is important for patients to follow their doctor’s instructions and avoid long-term use without medical advice.

General data about IBUTIN 300mg

Substance: trimebutin

Date of last drug list: 01-06-2025

Commercial code: W42800002

Concentration: 300mg

Pharmaceutical form: prolonged tablets

Quantity: 20

Product type: generic

Price: 53.69 RON

Prescription restrictions: P-6L - Medicines prescription that isn't retained in the pharmacy (can be renewed); the prescription can be used for 6 months from the moment of release.

Marketing authorisation

Manufacturer: GALENICA PHARMACEUTICAL INDUSTRY S.A. - GRECIA

Holder: ZENTIVA S.A. - ROMANIA

Number: 12413/2019/02

Shelf life: 2 years

Pharmaceutical forms available for trimebutin

Concentrations available for trimebutin

100mg, 200mg, 24mg/5ml, 300mg

Other substances similar to trimebutin

Compensation lists for IBUTIN 300mg ZENTIVA

D - Sublist D with 20% discount from the reference price

Price

Copayment

Patient

53.69 RON

5.92 RON

47.77 RON