IBUPROFEN/CLORHIDRAT DE FENILEFRINA ZENTIVA 200mg / 5mg film-coated tablets medication leaflet

M01AE51 • ibuprofen + phenylephrine • Musculo-skeletal system | Antiinflammatory and antirheumatic products, non-steroids | Propionic acid derivatives

Ibuprofen and phenylephrine are active ingredients used in combination to treat cold and flu symptoms such as fever, headaches, muscle pain, and nasal congestion. This combination is effective in relieving discomfort associated with respiratory infections, providing both anti-inflammatory and decongestant effects.

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation, pain, and fever by inhibiting the synthesis of prostaglandins, substances involved in the inflammatory process. Phenylephrine is a nasal decongestant that works by constricting blood vessels in the nasal mucosa, reducing inflammation and congestion, thereby improving breathing.

Although this combination is effective, its use should be approached with caution. Ibuprofen may cause gastrointestinal side effects, such as stomach irritation, heartburn, or ulcers, especially with long-term use. Phenylephrine may cause insomnia, agitation, or increased blood pressure, particularly in sensitive individuals or those with cardiovascular conditions. It is important not to exceed the recommended dose.

This combination is available over the counter, but patients should follow the usage instructions and avoid long-term use. If symptoms persist for more than a few days or worsen, medical advice is necessary. Individuals with high blood pressure, cardiovascular diseases, or other chronic conditions should consult a doctor before use.