Indicated for: pain and inflammation
Route of administration: oral
Substance: ibuprofen + caffeine (nonsteroidal anti-inflammatory drug + analgesic and antipyretic)
ATC: M01AE51 (Musculo-skeletal system | Antiinflammatory and antirheumatic products, non-steroids | Propionic acid derivatives)
This medicine may have important interactions with other medicines.
This medicine may affect the kidneys.
Use during pregnancy only on medical advice.
This medicine may increase the risk of bleeding.
This medicine may increase the risk of ulcer or gastrointestinal bleeding.
Ibuprofen and caffeine are active ingredients used in combination to treat mild to moderate pain, such as headaches, migraines, dental pain, or muscle pain. This combination is effective due to the synergistic effect of the two components, providing faster and more intense pain relief.
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation, pain, and fever by inhibiting the synthesis of prostaglandins, substances involved in the inflammatory process. Caffeine acts as a stimulant on the central nervous system and enhances the absorption of ibuprofen, thereby increasing its effectiveness. Additionally, caffeine can reduce the feeling of fatigue associated with pain.
Although this combination is effective, its use should be approached with caution. Ibuprofen may cause gastrointestinal side effects, such as stomach irritation, heartburn, or ulcers, especially with long-term use. Caffeine may cause insomnia, agitation, or palpitations, particularly in sensitive individuals. It is important not to exceed the recommended dose.
This combination is available over the counter, but patients should follow the usage instructions and avoid long-term use. If pain persists for more than a few days or worsens, medical advice is necessary. Individuals with chronic conditions or those taking other medications should consult a doctor before use.