Indicated for: type 2 diabetes mellitus
Substance: metformin (biguanide antidiabetic)
ATC: A10BA02 (Alimentary tract and metabolism | Blood glucose lowering drugs, excl. insulins | Biguanides)
Metformin is a medication primarily used to treat type 2 diabetes. It is an oral antidiabetic from the biguanide class that helps lower blood glucose levels by improving insulin sensitivity and reducing glucose production by the liver. Metformin also slows the absorption of glucose from the digestive tract.
This medication is commonly used as a first-line treatment for type 2 diabetes, especially in overweight or obese patients, as it does not cause weight gain. In some cases, it is also used for polycystic ovary syndrome (PCOS) due to its effects on glucose and insulin metabolism.
Side effects may include nausea, diarrhea, abdominal pain, or loss of appetite, particularly at the start of treatment. In rare cases, it can cause lactic acidosis, a serious complication, especially in patients with kidney impairment or other severe conditions. It is important to take metformin as prescribed by a doctor, with regular monitoring of kidney function.