Indicated for: gastroesophageal reflux; acid dyspepsia
Route of administration: oral
Substance: sodium alginate + sodium hydrogen carbonate + calcium carbonate (alginate anti-reflux agent + antacid)
ATC: A02BX13 (Alimentary tract and metabolism | Drugs for peptic ulcer and gastro-oesophageal reflux disease (gord) | Other drugs for peptic ulcer and gastro-oesophageal reflux disease (gord))
The combination of sodium alginate, sodium bicarbonate (natrii hydrogeni carbonas), and calcium carbonate is used to treat symptoms of gastroesophageal reflux, such as heartburn and acid regurgitation. It works by forming a protective barrier in the stomach, preventing acid reflux into the esophagus.
Sodium alginate is a natural derivative from seaweed that, when in contact with stomach acid, forms a viscous gel. This gel floats on top of the stomach contents, acting as a physical barrier that prevents acid from reaching the esophagus.
Sodium bicarbonate helps neutralize stomach acid, providing rapid relief from heartburn. Additionally, the reaction between bicarbonate and stomach acid produces carbon dioxide, which helps lift the alginate gel, enhancing the effectiveness of the protective barrier.
Calcium carbonate also has an acid-neutralizing effect, providing additional relief from reflux symptoms. Furthermore, it contributes to strengthening the protective barrier formed by the alginate.
This combination is available as oral suspensions or chewable tablets and is usually taken after meals and before bedtime. It is important for patients to follow the doctor’s or package instructions to achieve maximum benefits.
Side effects are rare and include bloating, nausea, or constipation. In very rare cases, allergic reactions may occur. This combination is not recommended for patients with hypercalcemia, severe renal impairment, or allergies to any of the components. Patients should avoid excessive consumption of fatty or acidic foods, which can worsen reflux symptoms.