Dose adjustment in renal impairment
Dose adjustment may be needed in kidney disease.
Leaflet FRAGMIN 5000UI / 0.2ml solution for injection
- Product code:
- W64849001
- Quantity:
- 10
- Indicated for:
- prevention and treatment of thromboembolism
- Route of administration:
- injectable
- Substance:
- dalteparin (anticoagulant)
- ATC
- B01AB04 — Blood and blood forming organs | Antithrombotic agents | Antithrombotic agents | Heparin group
Dalteparin is an anticoagulant from the low molecular weight heparin (LMWH) class, used for the prevention and treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE). It is also indicated for preventing thromboembolic complications in patients with unstable angina or non-Q-wave myocardial infarction and for preventing clot formation in cancer patients.
Dalteparin works by inhibiting factor Xa and thrombin, thereby reducing blood clot formation. It is administered as subcutaneous injections, with the dosage adjusted based on body weight and the patient's condition.
Side effects may include bleeding, hematomas at the injection site, thrombocytopenia (low platelet count), or allergic reactions. It is contraindicated in patients with active bleeding, heparin-induced thrombocytopenia, or hypersensitivity to dalteparin. It should be used cautiously in patients with renal impairment.
Dalteparin works by inhibiting factor Xa and thrombin, thereby reducing blood clot formation. It is administered as subcutaneous injections, with the dosage adjusted based on body weight and the patient's condition.
Side effects may include bleeding, hematomas at the injection site, thrombocytopenia (low platelet count), or allergic reactions. It is contraindicated in patients with active bleeding, heparin-induced thrombocytopenia, or hypersensitivity to dalteparin. It should be used cautiously in patients with renal impairment.
General data about FRAGMIN 5000UI / 0.2ml
- Substance:
- dalteparin
- Date of latest medicines list:
- 01-09-2026
- Product code:
- W64849001
- Concentration:
- 5000UI / 0.2ml
- Pharmaceutical form:
- solution for injection
- Packing volume:
- 0,2ml
- Product type:
- Original
- Price:
- 191.71 RON
- Prescription status:
- P-RF — Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.
Concentrations available for dalteparin
- 10000UI/0.4ml
- 10000UI/ml
- 12500UI/0.5ml
- 15000UI/0.6ml
- 18000UI/0.72ml
- 25000UI/ml
- 2500UI/0.2ml
- 5000UI/0.2ml
- 7500UI/0.3ml
Precautions:
Major drug interactions
This medicine may have important interactions with other medicines.
Additional monitoring
This medicine is subject to additional monitoring.
Breastfeeding warning
Use during breastfeeding only on medical advice.
Pregnancy warning
Use during pregnancy only on medical advice.
Bleeding risk
This medicine may increase the risk of bleeding.
Compensation lists for FRAGMIN 5000UI / 0.2ml Pfizer
B - Sublist B with 50% discount from the reference price
- Price
- 191.71 RON
- Copayment
- 60.35 RON
- Patient
- 131.36 RON
NHP 9.4 (C2) - Kidney transplant, combined kidney and pancreas transplant
- Price
- 191.71 RON
- Copayment
- 191.71 RON
- Patient
- 0.00 RON