Fertility warning
This medicine may affect fertility.
Leaflet EVOLTA 1mg / ml concentrate for solution for injection / infusion
- Product code:
- W51487001
- Quantity:
- 3
- Indicated for:
- leukemia
- Route of administration:
- injectable / infusion
- Substance:
- clofarabine (antineoplastic agent)
- ATC
- L01BB06 — Antineoplastic and immunomodulating agents | Antimetabolites | Purine analogues
Precautions:
Dose adjustment in hepatic impairment
Dose adjustment may be needed in liver disease.
Cytotoxic / special handling
Handle with special care.
Contraception required
Effective contraception is required during treatment.
Contraindicated during breastfeeding
Do not use this medicine while breastfeeding.
Contraindicated during pregnancy
Do not use this medicine during pregnancy.
Hepatotoxicity
This medicine may affect the liver.
Major drug interactions
This medicine may have important interactions with other medicines.
Myelosuppression / agranulocytosis
This medicine may lower blood cell counts.
Additional monitoring
This medicine is subject to additional monitoring.
Requires periodic laboratory tests
Periodic laboratory tests may be required during treatment.
Severe skin reactions
Stop taking the medicine and seek urgent medical help if a severe rash occurs.
Clofarabine is an antineoplastic agent used for the treatment of acute lymphoblastic leukemia in children and young adults who have not responded to other therapies. It works by inhibiting DNA and RNA synthesis in cancer cells, thereby preventing their proliferation.
The medication is administered intravenously, as directed by a doctor, usually as part of a treatment cycle. It is important for patients to undergo regular check-ups to monitor hematologic function and other effects of the therapy.
Patients should be aware of potential side effects, such as nausea, fever, or decreased blood cell counts. It is important to inform the doctor of any unusual symptoms.
Common side effects include nausea, fever, and decreased blood cell counts. In rare cases, severe reactions such as liver failure or severe infections may occur. Patients should be informed of these risks before use.
The medication is administered intravenously, as directed by a doctor, usually as part of a treatment cycle. It is important for patients to undergo regular check-ups to monitor hematologic function and other effects of the therapy.
Patients should be aware of potential side effects, such as nausea, fever, or decreased blood cell counts. It is important to inform the doctor of any unusual symptoms.
Common side effects include nausea, fever, and decreased blood cell counts. In rare cases, severe reactions such as liver failure or severe infections may occur. Patients should be informed of these risks before use.
General data about EVOLTA 1mg / ml
- Substance:
- clofarabine
- Date of latest medicines list:
- 01-07-2013
- Product code:
- W51487001
- Concentration:
- 1mg / ml
- Pharmaceutical form:
- concentrate for solution for injection / infusion
- Quantity:
- 3
- Product type:
- Original
- Prescription status:
- S — Medicines dispensed with a restricted medical prescription, reserved for use in certain specialized fields.