Leaflet ENSTILUM 50mcg / 0.5mg / g cutaneous foam

Indicated for: psoriasis

Route of administration: cutaneous

Substance: calcipotriol + betamethasone (immunomodulator + glucocorticoid)

ATC: D05AX52 (Dermatologicals | Antipsoriatics for topical use | Other antipsoriatics for topical use)

Precautions:
Glaucoma warning
Glaucoma warning

Use caution if you have glaucoma or increased eye pressure.

Avoid milk, calcium, iron, or antacids
Avoid milk, calcium, iron, or antacids

Do not take with milk, calcium, iron, magnesium, or antacids if separation is recommended.

Avoid live vaccines
Avoid live vaccines

Avoid live vaccines during treatment if contraindicated.

Hyperglycemia
Hyperglycemia

This medicine may increase blood sugar.

Immunosuppression / infection risk
Immunosuppression / infection risk

This medicine may increase the risk of infections.

Breastfeeding warning
Breastfeeding warning

Use during breastfeeding only on medical advice.

Pregnancy warning
Pregnancy warning

Use during pregnancy only on medical advice.

Withdrawal / do not stop abruptly
Withdrawal / do not stop abruptly

Do not stop treatment abruptly without medical advice.

Calcipotriol and betamethasone are used together for the treatment of plaque psoriasis, a chronic skin condition characterized by red patches covered with whitish scales. This combination reduces inflammation, itching, and slows down the excessive growth of skin cells.

Calcipotriol is a vitamin D analog that helps normalize the cell regeneration process, while betamethasone is a potent corticosteroid that reduces inflammation and suppresses local immune reactions.

The treatment is applied topically, usually in the form of an ointment or gel, and is intended for short-term use to avoid corticosteroid-related side effects. It is important to avoid application on the face, skin folds, or areas with thin skin.

Side effects may include local irritation, burning sensation, or itching. Long-term use can lead to skin thinning or other corticosteroid-related complications.

General data about ENSTILUM 50mcg / 0.5mg / g

  • Substance: calcipotriol + betamethasone
  • Date of latest medicines list: 01-06-2026
  • Product code: W62934001
  • Concentration: 50mcg / 0.5mg / g
  • Pharmaceutical form: cutaneous foam
  • Quantity: 1
  • Product type: Original
  • Price: 196.49 RON
  • Prescription status: P-RF - Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.

Marketing authorisation

  • Manufacturer: COLEP LAUPHEIM GMBH & CO. KG - GERMANIA
  • Holder: LEO PHARMA A/S - DANEMARCA
  • Number: 14258/2022/01
  • Shelf life: 2 years-dupa ambalarea dupa comercializare;after the first opening-6 months

Pharmaceutical forms available for calcipotriol + betamethasone

Concentrations available for calcipotriol + betamethasone

  • 0.5mg/g
  • 50mcg/0.5mg/g

Compensation lists for ENSTILUM 50mcg / 0.5mg / g LEO Pharma

B - Sublist B with 50% discount from the reference price

Price

Copayment

Patient

196.49 RON

85.28 RON

111.21 RON