Medicine information EMEND 125mg / 80mg capsules
- Product code:
- W64642001
- Quantity:
- 1
- Indicated for:
- chemotherapy-induced nausea and vomiting
- Route of administration:
- oral
- Substance:
- aprepitant (antiemetic)
- ATC
- A04AD12 — Alimentary tract and metabolism | Antiemetics and antinauseants | Antiemetics and antinauseants | Other antiemetics
Aprepitant is a neurokinin-1 (NK1) receptor antagonist used in the prevention of chemotherapy-induced or postoperative nausea and vomiting. It works by blocking NK1 receptors in the central nervous system, thereby preventing the effects of substance P, a neurotransmitter involved in the vomiting reflex.
Aprepitant is administered orally, usually in combination with other antiemetic medications such as corticosteroids and 5-HT3 receptor antagonists. It is commonly used in chemotherapy regimens with high emetogenic potential.
Common side effects include fatigue, constipation, diarrhea, and loss of appetite. In rare cases, allergic reactions or elevated liver enzymes may occur.
Aprepitant is an important therapeutic option for patients undergoing chemotherapy, helping to improve treatment tolerance and maintain their quality of life.
Aprepitant is administered orally, usually in combination with other antiemetic medications such as corticosteroids and 5-HT3 receptor antagonists. It is commonly used in chemotherapy regimens with high emetogenic potential.
Common side effects include fatigue, constipation, diarrhea, and loss of appetite. In rare cases, allergic reactions or elevated liver enzymes may occur.
Aprepitant is an important therapeutic option for patients undergoing chemotherapy, helping to improve treatment tolerance and maintain their quality of life.
General data about EMEND 125mg / 80mg
- Substance:
- aprepitant
- Date of latest medicines list:
- 01-10-2026
- Product code:
- W64642001
- Strength:
- 125mg / 80mg
- Pharmaceutical form:
- capsules
- Quantity:
- 1
- Product type:
- Original
- Price:
- 92.68 RON
- Prescription status:
- P-RF — Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.
Strengths available for aprepitant
- 125mg
- 125mg/80mg
- 40mg
- 80mg
Official documents
The correspondence between the document and the displayed text is unconfirmed.
- Source institution
- EMA
- Document language
- English
- Source record: first published
- 12/08/2009
- Source record: last updated
- 24/10/2025