DIPPERAM HCT 10mg / 160mg / 12.5mg film-coated tablets medication leaflet

C09DX01 • amlodipine + valsartan + hydrochlorothiazide • Cardiovascular system | Angiotensin II receptor blockers (ARBs), combinations | Angiotensin ii receptor blockers (arbs), other combinations

The combination of amlodipine, valsartan, and hydrochlorothiazide is used to treat essential hypertension (high blood pressure) in patients who cannot control their blood pressure with a combination of two medications. This triple therapy helps lower blood pressure and prevent cardiovascular complications, such as heart attack or stroke.

- Amlodipine is a calcium channel blocker that relaxes blood vessels, improving blood flow and lowering blood pressure.
- Valsartan is an angiotensin II receptor blocker (ARB) that blocks the effects of angiotensin II, a hormone that causes blood vessel constriction, thereby helping to lower blood pressure.
- Hydrochlorothiazide is a thiazide diuretic that helps eliminate excess salt and water from the body, reducing blood volume and, consequently, blood pressure.

This combination is indicated for patients requiring more intensive therapy to achieve optimal blood pressure control. Through the synergistic action of the three components, the treatment provides more effective blood pressure reduction.

Common side effects include dizziness, headache, swelling (especially in the ankles), nausea, fatigue, muscle cramps, or dry mouth. In rare cases, allergic reactions, severe hypotension, electrolyte imbalances (such as low potassium levels), or kidney impairment may occur.

Patients should strictly follow their doctor’s instructions regarding dosage and avoid excessive salt or alcohol consumption. It is important to inform the doctor about other medications being taken or pre-existing conditions, such as kidney or liver impairment or diabetes. Regular monitoring of blood pressure and blood tests is essential to prevent complications.