Leaflet DILORYM 25mg / 7.5mg film-coated tablets


Indicated for: heart failure

Route of administration: oral

Substance: carvedilol + ivabradine (beta blocker + cardiac If-current inhibitor)

ATC: C07FX06 (Cardiovascular system | Beta blocking agents, other combinations)

Precautions:
Dizziness / vertigo
Dizziness / vertigo

This medicine may cause dizziness or vertigo.

Hypotension / fall risk
Hypotension / fall risk

May lower blood pressure and increase the risk of falls.

Elderly warning
Elderly warning

Older people may have an increased risk of side effects.

Carvedilol and ivabradine are used together for the treatment of chronic heart failure in patients with elevated heart rates despite optimal therapy. This combination combines the effects of a beta-blocker (carvedilol) and a sinus node inhibitor (ivabradine), helping to reduce heart rate and improve cardiac function.

Carvedilol helps reduce the workload on the heart by relaxing blood vessels and lowering blood pressure, while ivabradine reduces heart rate by acting on the sinus node. This combination is particularly indicated for patients who cannot tolerate high doses of beta-blockers.

The medications are taken orally as directed by a doctor, and the dosage is adjusted based on the patient's response. Regular monitoring is essential to assess the effectiveness of the treatment and detect potential side effects.

Side effects may include dizziness, fatigue, bradycardia, low blood pressure, and, in rare cases, visual disturbances. Patients should inform their doctor of any unusual symptoms or adverse reactions.

General data about DILORYM 25mg / 7.5mg

  • Substance: carvedilol + ivabradine
  • Date of last drug list: 16-08-2017
  • Commercial code: W63658005
  • Concentration: 25mg / 7.5mg
  • Pharmaceutical form: film-coated tablets
  • Quantity: 112
  • Product type: generic
  • Prescription restrictions: P-6L - Medicines prescription that isn't retained in the pharmacy (can be renewed); the prescription can be used for 6 months from the moment of release.

Marketing authorisation

  • Manufacturer: LES LABORATOIRES SERVIER INDUSTRIE - FRANTA
  • Holder: EGIS PHARMACEUTICALS PLC - UNGARIA
  • Number: 9859/2017/05
  • Shelf life: 2 years

Concentrations available for carvedilol + ivabradine

  • 12.5mg/5mg
  • 12.5mg/7.5mg
  • 25mg/5mg
  • 25mg/7.5mg
  • 6.25mg/5mg
  • 6.25mg/7.5mg