Leaflet CYCLO-PROGYNOVA 2mg / 0.5mg sugar-coated tablets
Indicated for: contraception
Route of administration: oral
Substance: estradiol + norgestrel (estrogen + hormonal contraceptive)
ATC: G03FB01 (Genito urinary system and sex hormones | Progestogens and estrogens in combination | Progestogens and estrogens, sequential preparations)
Use during breastfeeding only on medical advice.
Use during pregnancy only on medical advice.
Estradiol and norgestrel are used together in hormone replacement therapy (HRT) for postmenopausal women. This combination helps alleviate menopausal symptoms and prevent osteoporosis in women at high risk.
Estradiol, an estrogen, replaces natural hormones that decline during menopause, reducing symptoms such as hot flashes, night sweats, vaginal dryness, and irritability. Norgestrel, a synthetic progestin, protects the uterine lining from excessive estrogen effects, preventing endometrial hyperplasia and reducing the risk of endometrial cancer.
This combination is effective for women with severe menopausal symptoms, providing a more stable hormonal balance. Norgestrel may also help regulate the menstrual cycle during the transition to menopause.
Side effects may include headaches, nausea, breast tenderness, mood changes, or water retention. In rare cases, more serious reactions such as blood clots, high blood pressure, or liver problems may occur, making regular medical monitoring essential.
Patients should strictly follow their doctor’s recommendations, and long-term use should be periodically evaluated to minimize risks and maximize treatment benefits.
General data about CYCLO-PROGYNOVA 2mg / 0.5mg
- Substance: estradiol + norgestrel
- Date of latest medicines list: 01-06-2026
- Product code: W64044001
- Concentration: 2mg / 0.5mg
- Pharmaceutical form: sugar-coated tablets
- Quantity: 21
- Product type: Original
- Price: 9.20 RON
- Prescription status: P-6L - Medicines dispensed with a medical prescription that is not retained by the pharmacy and may be renewed; the prescription may be used for 6 months from the date of issue.
Compensation lists for CYCLO-PROGYNOVA 2mg / 0.5mg Bayer
B - Sublist B with 50% discount from the reference price
Price
Copayment
Patient
9.20 RON
4.60 RON
4.60 RON