COMBOGESIC 500mg / 150mg film-coated tablets medication leaflet

N02BE51 • paracetamol + ibuprofen • Nervous system | Other analgesics and antipyretics | Anilides

Paracetamol + ibuprofen is a combination medication used to treat moderate to severe pain and fever. This combination is effective in relieving pain and inflammation and is commonly used for conditions such as headaches, dental pain, muscle pain, postoperative pain, or fever associated with infections.

Paracetamol acts as an analgesic and antipyretic, reducing pain and fever, while ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID), reduces inflammation and pain by inhibiting prostaglandin production. The combination of the two drugs provides a synergistic effect, making it more effective than taking each drug separately.

Side effects may include nausea, heartburn, dizziness, or, in rare cases, allergic reactions. Long-term use or high doses may increase the risk of liver damage (due to paracetamol) or gastric irritation and ulcers (due to ibuprofen). It is important to take this combination as directed by a doctor or pharmacist.