Hepatotoxicity
This medicine may affect the liver.
Leaflet COMBIFEXIN 200mg / 500mg film-coated tablets
- Product code:
- W70066003
- Quantity:
- 10
- Indicated for:
- pain; fever
- Route of administration:
- oral
- Substance:
- ibuprofen + paracetamol (nonsteroidal anti-inflammatory drug + analgesic and antipyretic)
- ATC
- M01AE51 — Musculo-skeletal system | Antiinflammatory and antirheumatic products | Antiinflammatory and antirheumatic products, non-steroids | Propionic acid derivatives
Precautions:
Major drug interactions
This medicine may have important interactions with other medicines.
Nephrotoxicity
This medicine may affect the kidneys.
Pregnancy warning
Use during pregnancy only on medical advice.
Bleeding risk
This medicine may increase the risk of bleeding.
Ulcer / gastrointestinal bleeding
This medicine may increase the risk of ulcer or gastrointestinal bleeding.
Ibuprofen and paracetamol are two active ingredients commonly used in combination to treat mild to moderate pain and fever. This combination is effective in relieving headaches, muscle pain, dental pain, menstrual pain, and other types of discomfort, providing complementary analgesic and antipyretic effects.
Paracetamol is an analgesic and antipyretic that reduces pain and fever, being well-tolerated by most patients. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation, pain, and fever by inhibiting the synthesis of prostaglandins, substances involved in the inflammatory process. Together, these substances provide more effective pain and inflammation relief than using either one alone.
Although this combination is effective, its use should be approached with caution. Ibuprofen may cause gastrointestinal side effects, such as stomach irritation, heartburn, or ulcers, especially with long-term use. Paracetamol, if overused, can harm the liver. It is important for patients to follow the recommended dosage and avoid alcohol consumption during treatment.
This combination is available over the counter, but patients should adhere to usage instructions and avoid long-term use without consulting a doctor. If pain or fever persists for more than a few days, medical advice is necessary to identify the cause and adjust the treatment.
Paracetamol is an analgesic and antipyretic that reduces pain and fever, being well-tolerated by most patients. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation, pain, and fever by inhibiting the synthesis of prostaglandins, substances involved in the inflammatory process. Together, these substances provide more effective pain and inflammation relief than using either one alone.
Although this combination is effective, its use should be approached with caution. Ibuprofen may cause gastrointestinal side effects, such as stomach irritation, heartburn, or ulcers, especially with long-term use. Paracetamol, if overused, can harm the liver. It is important for patients to follow the recommended dosage and avoid alcohol consumption during treatment.
This combination is available over the counter, but patients should adhere to usage instructions and avoid long-term use without consulting a doctor. If pain or fever persists for more than a few days, medical advice is necessary to identify the cause and adjust the treatment.
General data about COMBIFEXIN 200mg / 500mg
- Substance:
- ibuprofen + paracetamol
- Date of latest medicines list:
- 01-04-2024
- Product code:
- W70066003
- Concentration:
- 200mg / 500mg
- Pharmaceutical form:
- film-coated tablets
- Quantity:
- 10
- Product type:
- Generic medicine
- Prescription status:
- OTC — Over the Counter = medicine that does not require a medical prescription.
Pharmaceutical forms available for ibuprofen + paracetamol
Concentrations available for ibuprofen + paracetamol
- 200mg/500mg
- 400mg/325mg