Indicated for: constipation
Route of administration: oral
Substance: prucalopride (5-HT4 receptor agonist; prokinetic agent)
ATC: A06AX05 (Alimentary tract and metabolism | Drugs for constipation | Other drugs for constipation)
Prucalopride is a medication used for the treatment of chronic constipation in patients for whom regular laxatives have not been effective.
It belongs to a class of drugs called selective 5-HT4 receptor agonists, which stimulate intestinal motility by increasing muscle contractions in the colon.
Prucalopride is particularly indicated for patients suffering from severe constipation associated with impaired intestinal transit.
The medication helps restore a normal rhythm of bowel movements, reducing abdominal discomfort and bloating.
Prucaloprid is usually taken once daily, and effects can be observed within a few days of starting treatment.
Common side effects include nausea, diarrhea, headaches, and dizziness, but these are usually mild and temporary.
It is important for patients to follow their doctor's recommendations and not exceed the prescribed dose.
Prucalopride is not recommended for use in children or adolescents and should be used with caution in patients with severe renal or hepatic conditions.
The medication is also contraindicated in cases of intestinal obstruction or active inflammatory bowel diseases.
Patients should inform their doctor about any other medications they are taking, as prucaloprid may interact with other treatments.
In the event of severe side effects, such as intense abdominal pain or symptoms of allergic reactions, immediate medical attention should be sought.