Leaflet CO-NEBILET 5mg / 12.5mg film-coated tablets

Indicated for: hypertension

Route of administration: oral

Substance: nebivolol + hydrochlorothiazide (beta blocker + diuretic)

ATC: C07BB12 (Cardiovascular system | Beta blocking agents and thiazides | Beta blocking agents, selective, and thiazides)

Precautions:
Dose adjustment in renal impairment
Dose adjustment in renal impairment

Dose adjustment may be needed in kidney disease.

Dizziness / vertigo
Dizziness / vertigo

This medicine may cause dizziness or vertigo.

Photosensitivity
Photosensitivity

Avoid excessive exposure to sunlight or UV radiation.

Hypotension / fall risk
Hypotension / fall risk

May lower blood pressure and increase the risk of falls.

Requires periodic laboratory tests
Requires periodic laboratory tests

Periodic laboratory tests may be required during treatment.

Elderly warning
Elderly warning

Older people may have an increased risk of side effects.

Electrolyte disturbances
Electrolyte disturbances

This medicine may change blood electrolyte levels.

Nebivolol and hydrochlorothiazide are used together to treat high blood pressure (hypertension). Nebivolol is a beta-blocker that helps relax blood vessels and reduce heart rate, thereby lowering blood pressure. Hydrochlorothiazide is a diuretic that helps remove excess water and salt from the body, reducing blood volume and blood pressure.

This combination is effective in reducing the risk of cardiovascular complications, such as heart attacks and strokes, in patients with hypertension. It is important to take the medication as prescribed by your doctor to achieve the best results.

Nebivolol is well-tolerated by most patients but may cause side effects such as fatigue, dizziness, or headaches. Hydrochlorothiazide may lead to potassium loss, requiring regular monitoring of electrolyte levels.

Patients should inform their doctor about any other medications they are taking, as this combination may interact with other treatments. Additionally, maintaining a healthy lifestyle, including a balanced diet and regular exercise, is essential to support the treatment of high blood pressure.

General data about CO-NEBILET 5mg / 12.5mg

  • Substance: nebivolol + hydrochlorothiazide
  • Date of latest medicines list: 01-06-2026
  • Product code: W54259002
  • Concentration: 5mg / 12.5mg
  • Pharmaceutical form: film-coated tablets
  • Quantity: 14
  • Product type: Original
  • Price: 18.94 RON
  • Prescription status: P-6L - Medicines dispensed with a medical prescription that is not retained by the pharmacy and may be renewed; the prescription may be used for 6 months from the date of issue.

Marketing authorisation

  • Manufacturer: BERLIN - CHEMIE AG - GERMANIA
  • Holder: MENARINI INTERNATIONAL OPERATIONS LUXEMBOURG S.A. - LUXEMBURG
  • Number: 5382/2013/02
  • Shelf life: 3 years

Concentrations available for nebivolol + hydrochlorothiazide

  • 5mg/12.5mg
  • 5mg/25mg