Leaflet CLOSTILBEGYT 50mg tablets
Product code: W01354001 Quantity: 10
Indicated for: infertility
Route of administration: oral
Substance: clomiphene (selective estrogen receptor modulator)
ATC: G03GB02 (Genito urinary system and sex hormones | Gonadotropins and other ovulation stimulants | Ovulation stimulants, synthetic)
Use during breastfeeding only on medical advice.
Use during pregnancy only on medical advice.
Clomifene (or clomiphene) is a medication primarily used to treat infertility in women. It is a selective estrogen receptor modulator (SERM) that stimulates ovulation by increasing the secretion of gonadotropins (follicle-stimulating hormone - FSH and luteinizing hormone - LH). It is indicated in cases of anovulation (lack of ovulation) or irregular ovulation, such as in polycystic ovary syndrome (PCOS).
Clomifene works by blocking estrogen receptors in the hypothalamus, which leads to increased secretion of FSH and LH by the pituitary gland. These hormones stimulate the development of ovarian follicles and the release of eggs, thereby increasing the chances of conception. The treatment is usually administered orally, starting on days 2-5 of the menstrual cycle, for 5 days.
While effective, clomifene can cause side effects. The most common include hot flashes, nausea, headaches, breast tenderness, and bloating. In rare cases, ovarian hyperstimulation syndrome (OHSS) may occur, causing severe abdominal pain and fluid accumulation in the abdomen. Additionally, clomifene use increases the likelihood of multiple pregnancies (twins or triplets).
Clomifene should be used as directed by a doctor, and patients should be monitored during treatment to assess ovarian response. It is important not to exceed the recommended duration of treatment (usually a maximum of 6 cycles), as prolonged use may increase the risk of complications. If severe side effects or unusual symptoms occur, immediate medical attention is necessary.
General data about CLOSTILBEGYT 50mg
- Substance: clomiphene
- Date of latest medicines list: 01-06-2026
- Product code: W01354001
- Concentration: 50mg
- Pharmaceutical form: tablets
- Quantity: 10
- Product type: Generic medicine
- Price: 94.35 RON
- Prescription status: P-RF - Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.
Compensation lists for CLOSTILBEGYT 50mg Egis
B - Sublist B with 50% discount from the reference price
Price
Copayment
Patient
94.35 RON
47.18 RON
47.17 RON