Indicated for: leukemia
Route of administration: infusion
Substance: clofarabine (antineoplastic agent)
ATC: L01BB06 (Antineoplastic and immunomodulating agents | Antimetabolites | Purine analogues)
This medicine may affect fertility.
Dose adjustment may be needed in liver disease.
Handle with special care.
Effective contraception is required during treatment.
Do not use this medicine while breastfeeding.
Do not use this medicine during pregnancy.
This medicine may affect the liver.
This medicine may have important interactions with other medicines.
This medicine may lower blood cell counts.
This medicine is subject to additional monitoring.
Periodic laboratory tests may be required during treatment.
Stop taking the medicine and seek urgent medical help if a severe rash occurs.
Clofarabine is an antineoplastic agent used for the treatment of acute lymphoblastic leukemia in children and young adults who have not responded to other therapies. It works by inhibiting DNA and RNA synthesis in cancer cells, thereby preventing their proliferation.
The medication is administered intravenously, as directed by a doctor, usually as part of a treatment cycle. It is important for patients to undergo regular check-ups to monitor hematologic function and other effects of the therapy.
Patients should be aware of potential side effects, such as nausea, fever, or decreased blood cell counts. It is important to inform the doctor of any unusual symptoms.
Common side effects include nausea, fever, and decreased blood cell counts. In rare cases, severe reactions such as liver failure or severe infections may occur. Patients should be informed of these risks before use.