Dose adjustment in renal impairment
Dose adjustment may be needed in kidney disease.
Leaflet CIPROLEN 500mg film-coated tablets
- Product code:
- W01289001
- Quantity:
- 10
- Indicated for:
- bacterial infections
- Route of administration:
- oral
- Substance:
- ciprofloxacin (fluoroquinolone antibiotic)
- ATC
- J01MA02 — Antiinfectives for systemic use | Quinolone antibacterials | Fluoroquinolones
Precautions:
Anaphylaxis
Risk of severe allergic reaction. Seek urgent medical help if serious symptoms occur.
Colitis / severe diarrhea
Seek medical advice if severe or persistent diarrhea occurs.
Avoid milk, calcium, iron, or antacids
Do not take with milk, calcium, iron, magnesium, or antacids if separation is recommended.
Photosensitivity
Avoid excessive exposure to sunlight or UV radiation.
Major drug interactions
This medicine may have important interactions with other medicines.
Neuropathy / neurotoxicity
This medicine may affect the nerves or nervous system.
Cardiac risk / QT prolongation / arrhythmias
This medicine may increase the risk of heart rhythm disturbances.
Seizure risk
This medicine may increase the risk of seizures.
Tendonitis / tendon rupture
Stop treatment and seek medical advice if tendon pain occurs.
Ciprofloxacin is an antibiotic from the fluoroquinolone class used to treat a wide range of bacterial infections. It is indicated for urinary tract infections, respiratory infections, gastrointestinal infections, skin and soft tissue infections, as well as certain bone and joint infections. It is also used in the treatment of anthrax.
Ciprofloxacin works by inhibiting DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication and repair, leading to bacterial destruction. It is available in tablet, injectable solution, and eye or ear drop forms.
Side effects may include nausea, diarrhea, headache, dizziness, or allergic reactions. In rare cases, it can cause tendinitis, tendon rupture, or severe reactions such as peripheral neuropathy. It is contraindicated in children, pregnant women, and patients with hypersensitivity to fluoroquinolones.
Ciprofloxacin works by inhibiting DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication and repair, leading to bacterial destruction. It is available in tablet, injectable solution, and eye or ear drop forms.
Side effects may include nausea, diarrhea, headache, dizziness, or allergic reactions. In rare cases, it can cause tendinitis, tendon rupture, or severe reactions such as peripheral neuropathy. It is contraindicated in children, pregnant women, and patients with hypersensitivity to fluoroquinolones.
General data about CIPROLEN 500mg
- Substance:
- ciprofloxacin
- Date of latest medicines list:
- 01-06-2026
- Product code:
- W01289001
- Concentration:
- 500mg
- Pharmaceutical form:
- film-coated tablets
- Quantity:
- 10
- Product type:
- Generic medicine
- Price:
- 17.90 RON
- Prescription status:
- P-RF — Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.
Pharmaceutical forms available for ciprofloxacin
Concentrations available for ciprofloxacin
- 0.3%
- 1000mg
- 100mg
- 100mg/10ml
- 100mg/50ml
- 10mg/ml
- 200mg/100ml
- 250mg
- 2mg/ml
- 3mg/ml
- 400mg/200ml
- 500mg
- 50mg/ml
- 750mg
Combinations with other substances
Compensation lists for CIPROLEN 500mg Helcor
A - Sublist A with 90% discount from the reference price
- Price
- 17.90 RON
- Copayment
- 15.13 RON
- Patient
- 2.77 RON
GX (C1) - GENERIC (used in compensation list, C1, for another diagnosis)
- Price
- 17.90 RON
- Copayment
- 16.66 RON
- Patient
- 1.24 RON
NHP 1.A (C2) - People with HIV/AIDS and post-exposure treatment
- Price
- 17.90 RON
- Copayment
- 16.66 RON
- Patient
- 1.24 RON