Leaflet CILOPEN 500mg / 500mg powder infusion solution


Indicated for: bacterial infections

Substance: imipenem + cilastatin (carbapenem antibiotic + statin lipid-lowering agent)

ATC: J01DH51 (Antiinfectives for systemic use | Other beta-lactam antibacterials | Carbapenems)

The combination of imipenem and cilastatin is an antibiotic used to treat severe bacterial infections, including respiratory, urinary, abdominal infections, or sepsis. Imipenem is a carbapenem antibiotic, and cilastatin prevents its degradation in the kidneys, enhancing its effectiveness.

The medication is administered via intravenous injection under the supervision of a specialist.

Side effects may include nausea, vomiting, diarrhea, skin rashes, or injection site reactions. In rare cases, severe allergic reactions or seizures may occur.

Patients should inform their doctor about any allergies or other medications they are taking. Pregnant or breastfeeding women should consult a specialist before use.

General data about CILOPEN 500mg / 500mg

  • Substance: imipenem + cilastatin
  • Date of last drug list: 01-05-2026
  • Commercial code: W54471006
  • Concentration: 500mg / 500mg
  • Pharmaceutical form: powder infusion solution
  • Quantity: 10
  • Product type: generic
  • Price: 416.87 RON
  • Prescription restrictions: P-RF - Medicines prescription that is retained in the pharmacy (not renewable).

Marketing authorisation

  • Manufacturer: TERAPIA SA - ROMANIA
  • Holder: TERAPIA SA - ROMANIA
  • Number: 13122/2020/09
  • Shelf life: 2 years;after reconstituting the solution-se utlizeaza imediat

Pharmaceutical forms available for imipenem + cilastatin

Concentrations available for imipenem + cilastatin

  • 250mg/250mg
  • 500mg/500mg

Combinations with other substances

Compensation lists for CILOPEN 500mg / 500mg Terapia

NHP 1.A (C2) - People with HIV/AIDS and post-exposure treatment

Price

Copayment

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416.87 RON

308.86 RON

108.01 RON

NHP 1.B (C2) - Tuberculosis

Price

Copayment

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416.87 RON

308.86 RON

108.01 RON

NHP 9.1 (C2) - Spinal cord transplant

Price

Copayment

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416.87 RON

308.86 RON

108.01 RON

NHP 9.2 (C2) - Heart transplant

Price

Copayment

Patient

416.87 RON

308.86 RON

108.01 RON