Dose adjustment in hepatic impairment
Dose adjustment may be needed in liver disease.
Leaflet CERVUGID 200mg / 500mg / 660000UI / 15mg ovules
- Product code:
- W08363002
- Quantity:
- 12
- Indicated for:
- mixed vaginal infections
- Route of administration:
- vaginal
- Substance:
- chloramphenicol + metronidazole + nystatin + hydrocortisone (antibacterial antibiotic + nitroimidazole antimicrobial + antifungal + glucocorticoid)
- ATC
- G01BAN1 — Genito urinary system and sex hormones | Antiinfectives/antiseptics in combination with corticosteroids | Antibiotics and corticosteroids
Precautions:
Anaphylaxis
Risk of severe allergic reaction. Seek urgent medical help if serious symptoms occur.
Breastfeeding warning
Use during breastfeeding only on medical advice.
Pregnancy warning
Use during pregnancy only on medical advice.
Chloramphenicol, metronidazole, nystatin, and hydrocortisone are used together in certain medications to treat complex infections involving bacteria, fungi, and inflammation. This combination is particularly indicated for skin, vaginal, or rectal infections where antimicrobial, antifungal, and anti-inflammatory actions are required.
Chloramphenicol is a broad-spectrum antibiotic that inhibits bacterial protein synthesis, effective against gram-positive and gram-negative bacteria. Metronidazole is an antimicrobial and antiprotozoal agent that acts against anaerobic bacteria and protozoa. Nystatin is an antifungal effective against fungal infections, particularly Candida albicans. Hydrocortisone is a corticosteroid with anti-inflammatory and antipruritic properties, reducing inflammation, swelling, and itching.
While this combination is effective, its use requires caution. Chloramphenicol may cause rare side effects, such as hypersensitivity or bone marrow aplasia. Metronidazole may cause nausea, dizziness, or allergic reactions. Nystatin is generally well-tolerated but may cause local irritation. Hydrocortisone, if used long-term, can lead to skin thinning, secondary infections, or suppression of the hypothalamic-pituitary-adrenal axis.
This combination should be used as directed by a doctor, and the duration of treatment should be limited to reduce the risk of side effects. It is important to avoid long-term use or application over large areas of the skin. If severe side effects or persistent symptoms occur, immediate medical attention is necessary.
Chloramphenicol is a broad-spectrum antibiotic that inhibits bacterial protein synthesis, effective against gram-positive and gram-negative bacteria. Metronidazole is an antimicrobial and antiprotozoal agent that acts against anaerobic bacteria and protozoa. Nystatin is an antifungal effective against fungal infections, particularly Candida albicans. Hydrocortisone is a corticosteroid with anti-inflammatory and antipruritic properties, reducing inflammation, swelling, and itching.
While this combination is effective, its use requires caution. Chloramphenicol may cause rare side effects, such as hypersensitivity or bone marrow aplasia. Metronidazole may cause nausea, dizziness, or allergic reactions. Nystatin is generally well-tolerated but may cause local irritation. Hydrocortisone, if used long-term, can lead to skin thinning, secondary infections, or suppression of the hypothalamic-pituitary-adrenal axis.
This combination should be used as directed by a doctor, and the duration of treatment should be limited to reduce the risk of side effects. It is important to avoid long-term use or application over large areas of the skin. If severe side effects or persistent symptoms occur, immediate medical attention is necessary.
General data about CERVUGID 200mg / 500mg / 660000UI / 15mg
- Substance:
- chloramphenicol + metronidazole + nystatin + hydrocortisone
- Date of latest medicines list:
- 01-08-2020
- Product code:
- W08363002
- Concentration:
- 200mg / 500mg / 660000UI / 15mg
- Pharmaceutical form:
- ovules
- Quantity:
- 12
- Product type:
- Generic medicine
- Price:
- 31.57 RON
- Prescription status:
- P-RF — Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.
Compensation lists for CERVUGID 200mg / 500mg / 660000UI / 15mg
C3 - Sublist C - section C3 (children, pregnant women and postpartum women) with 100% discount from the reference price
- Price
- 49.71 RON
- Copayment
- 49.71 RON
- Patient
- 0.00 RON