Leaflet CEREX 500mg film-coated tablets

Product code:
W59424001
Quantity:
120
Indicated for:
cancer
Route of administration:
oral
Substance:
capecitabine (antimetabolite antineoplastic)
ATC
L01BC06 — Antineoplastic and immunomodulating agents | Antimetabolites | Pyrimidine analogues

Precautions:

Fertility warning

Fertility warning

This medicine may affect fertility.

Dose adjustment in hepatic impairment

Dose adjustment in hepatic impairment

Dose adjustment may be needed in liver disease.

Cytotoxic / special handling

Cytotoxic / special handling

Handle with special care.

Contraception required

Contraception required

Effective contraception is required during treatment.

Contraindicated during breastfeeding

Contraindicated during breastfeeding

Do not use this medicine while breastfeeding.

Contraindicated during pregnancy

Contraindicated during pregnancy

Do not use this medicine during pregnancy.

Hepatotoxicity

Hepatotoxicity

This medicine may affect the liver.

Major drug interactions

Major drug interactions

This medicine may have important interactions with other medicines.

Myelosuppression / agranulocytosis

Myelosuppression / agranulocytosis

This medicine may lower blood cell counts.

Additional monitoring

Additional monitoring

This medicine is subject to additional monitoring.

Requires periodic laboratory tests

Requires periodic laboratory tests

Periodic laboratory tests may be required during treatment.

Severe skin reactions

Severe skin reactions

Stop taking the medicine and seek urgent medical help if a severe rash occurs.

Genetic test recommended

Genetic test recommended

A genetic test may be needed before treatment.

Capecitabine is a chemotherapy medication used to treat various types of cancer, including colon, rectal, breast, and stomach cancer. It is a prodrug, meaning it is converted in the body into its active form, 5-fluorouracil (5-FU), which interferes with DNA and RNA synthesis in cancer cells.

Capecitabine is taken orally in tablet form, making it more convenient than other forms of chemotherapy that require intravenous administration. Treatment is usually given in cycles, and the dosage is adjusted based on the patient's weight, overall health, and the type of cancer being treated.

The medication can be used alone or in combination with other chemotherapy drugs or targeted therapies. It is important for patients to strictly follow their doctor's instructions and report any side effects or unusual symptoms.

Common side effects include nausea, vomiting, diarrhea, fatigue, and hand-foot syndrome (redness, swelling, and pain in the palms and soles). In rare cases, more severe complications such as bone marrow suppression or cardiac toxicity may occur. Regular monitoring is essential to ensure the safety and effectiveness of the treatment.

General data about CEREX 500mg

Substance:
capecitabine
Date of latest medicines list:
01-06-2026
Product code:
W59424001
Concentration:
500mg
Pharmaceutical form:
film-coated tablets
Quantity:
120
Product type:
Generic medicine
Price:
422.51 RON
Prescription status:
P-RF — Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.

Marketing authorisation

Manufacturer:
REMEDICA LTD. - CIPRU
Holder:
TERAPIA SA - ROMANIA
Number:
10211/2017/01
Shelf life:
3 years

Concentrations available for capecitabine

  • 150mg
  • 300mg
  • 500mg

Compensation lists for CEREX 500mg Terapia

NHP 3 (C2) - NHP oncology

Price
422.51 RON
Copayment
421.16 RON
Patient
1.35 RON