Leaflet CADUET 10mg / 10mg film-coated tablets

Indicated for: dyslipidemia; hypertension

Substance: atorvastatin + amlodipine (statin lipid-lowering agent + calcium channel blocker)

ATC: C10BX03 (Cardiovascular system | Lipid modifying agents, combinations | Lipid modifying agents in combination with other drugs)

The combination of atorvastatin and amlodipine is used for the treatment of patients with dyslipidemia and hypertension or other cardiovascular conditions. Atorvastatin is an HMG-CoA reductase inhibitor that lowers LDL cholesterol and triglyceride levels while increasing HDL cholesterol. Amlodipine is a calcium channel blocker that helps relax blood vessels and lower blood pressure.

This combination is administered orally, usually once daily, with the dosage adjusted based on the patient's needs and response to treatment. It is particularly indicated for patients at high cardiovascular risk who require both lipid and blood pressure control.

Common side effects include headaches, dizziness, peripheral edema, nausea, and muscle pain. In rare cases, severe adverse reactions such as rhabdomyolysis, liver failure, or allergic reactions may occur.

Patients taking this combination should undergo regular monitoring for liver function, lipid levels, and blood pressure. The atorvastatin and amlodipine combination provides a convenient and effective solution for managing overall cardiovascular risk, helping to prevent major cardiovascular events.